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Year : 1996  |  Volume : 44  |  Issue : 2  |  Page : 67--70

Infantile spasms : electroclinical syndrome.


Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560 029, India

Correspondence Address:
GN Dakshinamurty
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560 029
India
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Source of Support: None, Conflict of Interest: None


PMID: 29542453

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Infantile spasms is an age specific seizure disorder which occurs in infancy or early childhood either as a part of an epileptic syndrome accompanied by hypsarrhythmia or as chronic spasms involving the axial musculature with mental retardation. Information about infantile spasms in the Indian literature is very sparse. 29 patients of infantile spasms seen over a period of 5 years at NIMHANS were evaluated in this study. EEG was abnormal in all, with classical/modified hypsarrhythmia pattern in 5.14 were cryptogenic and the rest were symptomatic with birth asphyxia as the commonest underlying cause. All were treated with anticonvulsants and in addition 20 children received ACTH/Steroids. They were followed for a mean period of 18 months. The clinical status at the end of the follow-up, serial EEG findings and response in relation to the underlying cause and mode of therapy are discussed.






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Online since 20th March '04
Published by Wolters Kluwer - Medknow