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Year : 2001  |  Volume : 49  |  Issue : 3  |  Page : 284--6

Serum cobalamin levels in dementias.


Department of Neurology, C.N. Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110 029, India., India

Correspondence Address:
M Tripathi
Department of Neurology, C.N. Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110 029, India.
India
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Source of Support: None, Conflict of Interest: None


PMID: 11593247

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The present study attempts to find a correlation between low serum B-12 levels and dementias. A total of 178 patients of dementia were seen at the cognitive disorder clinic from 1996 to 1998. Serum B-12 levels were studied in 100 patients. 15 patients (39.5%) of Alzheimer's dementia had reduced B-12 levels, while only 5 patients (13.9%) with vascular dementias and 3 patients (11.5%) with other types of dementias had reduced levels. The incidence of low serum B-12 was statistically significant in the Alzheimer's group when compared with the other groups, individually as well as combined together (p<0.05). The aetiopathogenesis and significance of these findings is discussed and the literature is reviewed.






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Online since 20th March '04
Published by Wolters Kluwer - Medknow