Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 362  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
    Next article
    Previous article
    Table of Contents

 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded324    
    Comments [Add]    
    Cited by others 15    

Recommend this journal


Year : 2002  |  Volume : 50  |  Issue : 1  |  Page : 27--32

Sarcoglycanopathies : a report of 25 cases.

Department of Neurology, Sir JJ Group of Hospitals and Grant Medical College, Mumbai, 400020, India., India

Correspondence Address:
S V Khadilkar
Department of Neurology, Sir JJ Group of Hospitals and Grant Medical College, Mumbai, 400020, India.
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 11960147

Rights and PermissionsRights and Permissions

Twenty five patients with sarcoglycanopathies were studied prospectively. 21 of them had mild phenotype. Muscle involvement was more pronounced in adductor and flexor groups of muscles of the limbs, hip adductor muscles being the weakest. The selective and differential weakness between weak hip adductors and stronger hip abductors resulted in the hip abduction sign in 64% of cases. Distal muscle involvement in lower limbs was seen in 92% of cases, but was mild and late in the course of the disease. 44% patients had winging of scapulae. Immunocytochemistry showed multiple sarcoglycan deficiencies in 84% patients. Primary beta and delta sarcoglycanopathy was seen in the remaining 16% cases. Secondary dystrophin reduction was seen in 44% patients and correlated with beta sarcoglycan deficiency but not with functional disability.


Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow