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   Case Report
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CASE REPORT
Year : 2006  |  Volume : 54  |  Issue : 1  |  Page : 89-90

Hemangioblastoma of hippocampus without von Hippel-Lindau disease: Case report and review of literature


Department of Neurosurgery, Graduate School of Medicine, Osaka City University, Osaka, Japan

Correspondence Address:
K Ohata
Department of Neurosurgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545 - 8585
Japan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.24718

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  Abstract 

A rare case of hemangioblastoma located in the region of hippocampus is reported. A 27-year-old female presented with a single episode of generalized convulsion. The vascular and cherry red color hemangioblastoma was resected by a temporo-zygomatic approach. There has been no recurrence of tumor at a follow-up of 11 years


Keywords: Cerebrum, hemangioblastoma, hippocampus


How to cite this article:
Ohata K, Takami T, Tsuyuguchi N, Hara M, Haque M. Hemangioblastoma of hippocampus without von Hippel-Lindau disease: Case report and review of literature. Neurol India 2006;54:89-90

How to cite this URL:
Ohata K, Takami T, Tsuyuguchi N, Hara M, Haque M. Hemangioblastoma of hippocampus without von Hippel-Lindau disease: Case report and review of literature. Neurol India [serial online] 2006 [cited 2019 Aug 25];54:89-90. Available from: http://www.neurologyindia.com/text.asp?2006/54/1/89/24718


Supratentorial hemangioblastomas are rare tumors. From 1902 to 2005, around 118 cases (excluding our case) have been reported in the literature.[1],[2],[3],[4],[5],[6],[7],[8],[9],[10] These tumors originated in various supratentorial locations with or without associated von Hippel-Lindau disease. We could not locate any report of hemangioblastoma located in the region of hippocampus. The management of the case is reported.


  Case Report Top


The 27-year-old right-handed female presented with a single episode of generalized convulsion. Fundoscopic examination, ultrasonography of the abdomen and the family history did not reveal any clinical feature of von Hippel Lindau disease.

Magnetic resonance imaging (MRI) showed a mixed intensity solid mass lesion in the right hippocampal gyrus extending in to the temporal horn of the lateral ventricle. The lesion measured 18 x 12 x 15 mm in size. The lesion enhanced on Gadolinium administration [Figure - 1]. Conventional angiography showed that the tumor was highly vascularized and a branch of the anterior choroidal artery fed the tumor [Figure - 2].

A cherry red highly vascular tumor was totally removed through a temporo-zygomatic approach on 21st October, 1994. Histology confirmed that the lesion was a hemangioblastoma [Figure - 3]. The postoperative course was uneventful. At a follow-up after 11 years, the patient is asymptomatic and investigations have revealed no tumor recurrence or presence of any other mass in the central nervous system or in any other organ.


  Discussion Top


Approximately 118 cases of supratentorial hemangioblastomas have been reported in the literature. The tumors have been identified in a variety of locations of the brain.[1],[2],[3],[4],[5],[6],[7],[8],[9],[10] In the analysis of 80 cases, the incidence of tumor in location depended on the volume of parenchyma of each location. The age ranged from 3- to 83-year old (average age 36.2 years) and there was a male predomination.[1] Association with von Hippel-Lindau disease is estimated to be 16% of all supratentorial hemangioblastomas,[1] which is almost similar to the coincidence (13.5-34.3%) of cerebellar hemangioblastomas and von Hippel-Lindau disease.[1] Although 13 cases of hemangioblastoma have been identified in the temporal lobe,[1],[2], [5],[6],[7],[8],[9],[10] hemangioblastoma limited to the hippocampus is not reported.

To our knowledge, this is the first case report of hemangioblastoma of the hippocampus.

 
  References Top

1.Taniguchi E, Kodama Y, Hotta T. A case of hemangioblastoma of the thalamus. No Shinkei Geka 1994;22:1085-9.  Back to cited text no. 1    
2.Sharma RR, Cast IP, O'Brien C. Supratentorial haemangioblastoma not associated with Von Hippel Lindau complex or polycythemia: Case report and literature review. Br J Neurosurg 1995;9:81-4.  Back to cited text no. 2  [PUBMED]  
3.Bielschowsky M. Zur Histologir und Pathologie der Gehirngeschwulste. Dtsch Z Nervenheilked 1902;22:54-99. Cited by Morello and Bianchi (ref. 3)  Back to cited text no. 3    
4.Loftus CM, Marquardt MD, Stein BM. Hemangioblastoma of the third ventricle. Neurosurgery 1984;15:67.  Back to cited text no. 4  [PUBMED]  
5.Bosch J, Vilalta J, Tintore M. Parkinsonian hemi-syndrome as the initial menifestation of supratentorial cystic hemangioblastoma in a patient with Von Hippel-Lindau disease. Revista de Neurologia.  Back to cited text no. 5    
6.Tarantino R, Isidori A, Raco A. Supratentorial hemangioblastoma in a patient with breast cancer. A case report. J Neurol Sci 2000;44:137-9.  Back to cited text no. 6    
7.Kato K, Utsunomiya A, Uenohara H. Hemangioblastoma of the optic nerve growing like a dumbbell through the optic canal: case report. No To Shinkei 2004;56:711-6.  Back to cited text no. 7    
8.Acikalin MF, Oner U, Tel N. Supratentorial hemangioblastoma: a case report and review of the literature. Arch Pathol Lab Med 2003;127:382-4.  Back to cited text no. 8    
9.Ikeda M, Asada M, Yamashita H. A case of suprasellar hemangioblastoma with thoracic meningioma. No Shinkei Geka 2001;29:679-83 (Japanese).  Back to cited text no. 9    
10.Prieto R, Roda JM. Hemangioblastoma of the lateral ventricle: case report and review of the literature. Neurocirugia (Astur) 2005;16:58-62.  Back to cited text no. 10  [PUBMED]  [FULLTEXT]


    Figures

[Figure - 1], [Figure - 2], [Figure - 3]

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3 Non-von Hippel-Lindau hemangioblastoma in the hippocampus: Characterization with time-resolved MRA using TRICKS sequence at 3T: A case report
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