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 CASE REPORT
Year : 2006  |  Volume : 54  |  Issue : 4  |  Page : 412--414

Ataxia and deafness in a young male: An unusual aetiology


Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi - 2, India

Correspondence Address:
N P Singh
D-II/356, Pandara Road, New Delhi - 110 003
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.28117

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We report here a case of 18 year old male with tremors of hands, deafness, tendency to fall while walking, drowsiness and double vision of total duration 1½ years. He had internuclear ophthalmoplegia, broken saccades, hypertonia and hyperreflexia of all four limbs, intention tremors, signs of gait and limb ataxia. Pupillary reactions and fundus examination were normal and signs of meningeal irritation or sensory neurological deficit were absent. MRI head and cervical spine with gadolinium enhancement revealed demyelination as evident from multiple oblong foci isointense on T1-weighted images and hyperintense on T2-weighted and fluid attenuated inversion recovery sequences in corpus callosum, sub-cortical white matter, right thalamus, pons and periaqueductal region of midbrain. Ill-defined linear hyperintense signals were observed in cervical spinal cord. No skeletal abnormality was noted in the skull or cervical spine. Oligoclonal bands were present in the cerebrospinal fluid. Brainstem auditory evoked potentials were abnormal, although visual evoked potentials were in normal range. A diagnosis of primary progressive multiple sclerosis (PPMS) was made fulfilling the revised criteria as laid down. In view of its presentation, it is a unique case of PPMS from India.






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