Atormac
brintellex
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 482  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (657 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed2771    
    Printed69    
    Emailed0    
    PDF Downloaded139    
    Comments [Add]    
    Cited by others 3    

Recommend this journal

 


 
LETTER TO EDITOR
Year : 2008  |  Volume : 56  |  Issue : 4  |  Page : 485-486

MRI diagnosis of neurolymphomatosis of the brachial plexus


Department of Radiodiagnosis, Command Hospital Air Force, Bangalore, India

Date of Acceptance05-Sep-2008

Correspondence Address:
Arti Chaturvedi
Department of Radiodiagnosis, Command Hospital Air Force, Bangalore
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.44817

Rights and Permissions



How to cite this article:
Chaturvedi A, Singh J P, Rastogi V. MRI diagnosis of neurolymphomatosis of the brachial plexus. Neurol India 2008;56:485-6

How to cite this URL:
Chaturvedi A, Singh J P, Rastogi V. MRI diagnosis of neurolymphomatosis of the brachial plexus. Neurol India [serial online] 2008 [cited 2020 Aug 11];56:485-6. Available from: http://www.neurologyindia.com/text.asp?2008/56/4/485/44817


Sir,

Neurolymphomatosis (NL) is a rare manifestation of lymphoma which is characterized by selective infiltration of cranial and peripheral nerves and roots by lymphoma cells. [1] We present the classical magnetic resonance imaging (MRI) findings of brachial plexopathy in a 15-year-old boy with Non-Hodgkin's Lymphoma (NHL) who presented with right arm weakness six months after complete remission.

MRI of the brachial plexus demonstrated thickening and hyperintensity of the C5 root and upper trunk of the right brachial plexus. There was also hyperintensity of the adjacent spinal cord [Figure 1A] and [Figure 1B]. Post Gadolinium images showed significant contrast enhancement of the involved trunk, nerve root and the spinal cord at C4-5 level [Figure 2] and [Figure 3]. A concomitant CSF examination revealed the presence of multiple, abnormal B-cell lymphocytes. In view of these typical MRI and CSF findings, a diagnosis of B-cell neurolymphomatosis involving the right brachial plexus was made and the patient was started on salvage chemotherapy.

Patients of NL commonly present with a progressive sensorimotor peripheral neuropathy, plexopathy or cranial neuropathy. A histopathological demonstration of malignant lymphocytes in the peripheral nerves is the gold standard for diagnosis but a biopsy may not always be possible or positive. [2] In such situations, MRI can be of immense diagnostic value by demonstrating diffuse neural thickening and enhancement and thus enabling an early diagnosis of NL. [1],[3]

 
  References Top

1.Baehring JM, Damek D, Martin EC, Betensky RA, Hochberg FH. Neurolymphomatosis. Neuro Oncol 2003;5:104-15.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Shibata-Hamaguchi A, Samuraki M, Furui E, Ishida C, Kitagawa S, Nakao S, et al . B-cell neurolymphomatosis confined to the peripheral nervous system. J Neurol Sci 2007;260:249-52.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Swarnkar A, Fukui MB, Fink DJ, Rao GR. MR imaging of brachial plexopathy in neurolymphomatosis. AJR Am J Roentgenol 1997;169:1189-90.   Back to cited text no. 3  [PUBMED]  [FULLTEXT]


    Figures

  [Figure 1A], [Figure 1B], [Figure 2], [Figure 3]

This article has been cited by
1 High-Resolution 3T MR Neurography of the Brachial Plexus and Its Branches, with Emphasis on 3D Imaging
A. Chhabra, G. K. Thawait, T. Soldatos, R. S. Thakkar, F. D. Grande, M. Chalian, J. A. Carrino
American Journal of Neuroradiology. 2013; 34(3): 486
[VIEW] | [DOI]
2 Increasing importance of 18F-FDG PET in the diagnosis of neurolymphomatosis
Salm, L.P. and Van Der Hiel, B. and Stokkel, M.P.M.
Nuclear Medicine Communications. 2012; 33(9): 907-916
[Pubmed]
3 Increasing importance of 18F-FDG PET in the diagnosis of neurolymphomatosis
Liesbeth P. Salm,Bernies Van der Hiel,Marcel P.M. Stokkel
Nuclear Medicine Communications. 2012; 33(9): 907
[Pubmed] | [DOI]



 

Top
Print this article  Email this article
Previous article Next article
Online since 20th March '04
Published by Wolters Kluwer - Medknow