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 CASE REPORT
Year : 2010  |  Volume : 58  |  Issue : 1  |  Page : 128--130

Dural based primary osteosarcoma in right fronto-temporal region:Case report with review of literature


1 Department of Pathology and Transfusion Medicine, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India
2 Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India
3 Department of Radiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India
4 Department of Neurosciences, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India

Correspondence Address:
Nandita Ghosal
Department of Pathology, Sri Sathya Sai Institute of Higher Medical Sciences, EPIP Area, Whitefield, Bangalore - 560 066
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.60428

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We report a case of primary dural based osteosarcoma in the right fronto-temporal convexity in a 43-year-old female who presented with a short history of seizure and headache. Radiologic evaluation revealed a well defined brightly enhancing extra-axial lesion in the right fronto-temporal region with a dural tail around the sylvian fissure. The overlying bone was uninvolved. Paraffin section of the tumor showed plump cells with moderate nuclear and cellular pleomorphism with eosinophilic extracellular material (osteiod) between the cells. At a few places, lace like osteiod was seen encasing individual cells signifying osteiod being formed by tumor cells. Immunohistochemistry for epithelial membrane antigen was focally positive and negative for S-100 protein and glial fibrillary acidic protein. A final histopathological diagnosis of dural based primary osteosarcoma of the right fronto-temporal region was rendered. To the best of our knowledge this will be the eighth such case in literature.






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