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Year : 2010  |  Volume : 58  |  Issue : 1  |  Page : 136-137

Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus

1 Department of Pediatric, Haseki Education and Research Hospital, Istanbul, Turkey
2 Department of Neurology,Haseki Education and Research Hospital, Istanbul, Turkey
3 Pediatric Neurology Unit, Haseki Education and Research Hospital, Istanbul, Turkey

Date of Acceptance23-Oct-2009
Date of Web Publication8-Mar-2010

Correspondence Address:
Nilgun Selcuk Duru
Department of Pediatric, Haseki Education and Research Hospital, Istanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.60401

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How to cite this article:
Duru NS, Acar H, Ayta S, Elevli M. Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus. Neurol India 2010;58:136-7

How to cite this URL:
Duru NS, Acar H, Ayta S, Elevli M. Bilateral carpal tunnel syndrome in a child with type 1 diabetes mellitus. Neurol India [serial online] 2010 [cited 2018 May 20];58:136-7. Available from:


Carpal tunnel syndrome (CTS) is a collection of symptoms associated with compression of the median nerve at the wrist. [1] It is extremely uncommon in pediatric age group.

An 11-year-old boy, a known case of type diabetes mellitus (DM) since the age of six years on insulin with poor control, presented with complaints of weakness of both hands and burning, tingling, numbness and pricking in the hands more so in the first three digits. Symptoms worsen with the movements of wrist. On examination, he showed partial weakness in both hands. Thenar atrophy was not present. Phallen's and Tinel's tests were positive bilaterally. The other system examination was normal. Laboratory test: Blood glucose was 411 mg/dl and HbA1c was 10.9% (normal, 3.5-6.9%). Neurophysiologic studies showed bilaterally prolonged median motor distal latency, slowing of sensory nerve conduction velocity with normal amplitude bilaterally in the wrist segment. Prolonged median nerve sensory peak latency compared to sensory peak latency of ulnar nerve was observed with stimulation at the ring finger compared to sensory peak latency of the ulnar nerve [Figure 1], [Table 1] and [Table 2]. These findings were consistent with bilateral moderate CTS. [2] Therefore, carpal tunnel surgery was not advised, instead, non-steroidal anti-inflammatory medications and activity modification were suggested as the initial treatment.

Carpal tunnel syndrome in patients with type 1 diabetes is an extremely rare condition in children and adolescents. In fact, only one case has been described till date. [3] The prevalence of CTS increases with the duration of diabetes. [1],[4] It has been suggested that diabetic polyneuropathy may cause endoneural ischemia and the median nerves become more susceptible to pressure. However, our patient presented with bilateral CTS only without polyneuropathy. Motor and sensory conduction studies were normal in our patient [Figure 1]. Other suggested pathophysiological mechanisms included increasing glycosylation of collagen and fibrosis, or thickening of synovium within the carpal tunnel. [1],[3]

In conclusion, this case demonstrates that the clinician must be alert to the possible diagnosis of CTS in children or adolescent with DM. Early diagnosis and treatment of CTS in these children is important to alleviate symptoms and improve living conditions.

  References Top

1.Singh R, Gamble G, Cundy T. Lifetime risk of symptomatic carpal tunnel syndrome in Type 1 diabetes. Diabet Med 2005;22:625-30.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]  
2.Karadað YS, Karadað O, Cicekli E, Oztürk S, Kiraz S, Ozbakýr S, et al. Severity of Carpal tunnel syndrome assessed with high frequency ultrasonography. Rheumatol Int. 2009 [In Press]  Back to cited text no. 2      
3.Kayali H, Kahraman S, Sirin S, Bedük A, Timurkaynak E. Bilateral carpal tunnel syndrome with type 1 diabetes mellitus in childhood. Pediatr Neurosurg 2003;38:262-4.  Back to cited text no. 3      
4.Gamstedt A, Holm-Glad J, Ohlson CG, Sundström M. Hand abnormalities are strongly associated with the duration of diabetes mellitus. Intern Med 1993;234:189-93.  Back to cited text no. 4      


  [Figure 1]

  [Table 1], [Table 2]

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2 Carpal tunnel syndrome in diabetics: A mirror for peripheral neuropathic status
Abdel-Monem, A. and Hamdy, H. and Amir, M. and Al-Sadek, A.M. and Abdulghani, K.O. and Hashem, S. and Abdel-Bar, A.
Egyptian Journal of Neurology, Psychiatry and Neurosurgery. 2012; 49(4): 323-327


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