Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 668  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
    Next article
    Previous article
    Table of Contents

 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded212    
    Comments [Add]    
    Cited by others 12    

Recommend this journal


Year : 2010  |  Volume : 58  |  Issue : 4  |  Page : 560--564

Comparison of 1 week versus 4 weeks of albendazole therapy in single small enhancing computed tomography lesion

1 Department of Pediatrics, Government Multi Speciality Hospital, Sector 16, Chandigarh- 160 015, India
2 Department of Radiology, Government Multi Speciality Hospital, Sector 16, Chandigarh- 160 015, India

Correspondence Address:
Neeraj Dhawan
H. No. 6144, MHC, Manimajra, Chandigarh- 160 101
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.68677

Rights and Permissions

Background : The appropriate duration of albendazole therapy in neurocysticercosis is uncertain. The observation in small uncontrolled randomized trials in children that short-course therapy (1 week) is as effective as the conventional regimen (4weeks) must be tested. Objective : To compare the efficacy of 1 and 4 weeks of albendazole therapy in children with single small enhancing computed tomographic lesion (SSECTL). Study Design: An open-labeled, randomized, clinical trial. Materials and Methods : One hundred twenty children with SSECTLs presenting with seizure. Intervention: The subjects were assigned to two groups using random tables: group A (n=58) received albendazole for 1 week and group B (n=62) for 4 weeks. All the subjects were followed up for 6 months. Results : The proportions of subjects with complete resolution of lesion in the two groups were similar (group A 63.8% versus group B 51.6%). The proportion of subjects in the two groups in whom the lesion calcified on follow up (group A 19% versus group B 24.2%) also did not differ significantly. The incidence of seizure recurrence during the 6-month follow-up period was also similar in both the groups (group A 9.6% versus group B 3.4%, P > 0.05). Conclusion : One week of albendazole therapy is as effective as 4 weeks of therapy in children with SSECTLs.


Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow