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Year : 2011  |  Volume : 59  |  Issue : 5  |  Page : 669--673

Pilot study on a fast postoperative programming approach to subthalamic nucleus stimulation in Parkinson's disease

1 Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China
2 Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China
3 Department of Neurology, Inselsptial, Bern University, Bern, Switzerland

Correspondence Address:
Wei Wang
Department of Neurosurgery, West China Hospital of Sichuan University, 610041 Chengdu, Sichuan Province
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.86538

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Objectives : T0 o evaluate the advantages and disadvantages of a fast post-operative screening method using deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson's disease. Materials and Methods : T0 wenty-four patients implanted with electrodes for STN-DBS were divided into two groups : G0 roup I received traditional programming and Group II was treated with the fast method. The time required for programming in each group and the treatment effects were analyzed. Results : S0 ignificant postoperative improvement of the Unified Parkinson's Disease Rating Scale III was achieved in the "off medication" and "on stimulation" condition in both the groups (Group I: 51.2% vs. Group II: 54.0%, P<0.05). The average time needed for programming, however, was significantly shorter in Group II as compared to Group I (P<0.05). Conclusions : T0 he new fast method can significantly reduce the time required to find a preliminary effective STN-DBS protocol in the early postoperative phase without sacrificing clinical efficacy.


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Online since 20th March '04
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