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Year : 2011  |  Volume : 59  |  Issue : 6  |  Page : 891--894

Unique case of postpartum cerebral angiopathy requiring surgical intervention: Case report and review of literature

Department of Neurosurgery, Louisiana State University Health Science Center, Shreveport, Louisiana, USA

Correspondence Address:
Anil Nanda
Department of Neurosurgery, Louisiana State University Health Sciences Center - Shreveport, 1501 Kings Highway, Shreveport, Louisiana 71103
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.91372

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Postpartum cerebral angiopathy (PPCA) is a rare form of reversible cerebral vasoconstriction syndrome. A 39-year-old female presented with a 5×6 cm left frontal intracerebral hemorrhage (ICH) and following an emergent neurosurgical evacuation of ICH, she developed a contralateral ICH and intraventricular hemorrhage. Her postoperative course was highlighted by the finding of diffuse bilateral segmental vasospasm on angiography and trans-cranial Doppler, left anterior cerebral artery region infarct and intractable elevated intracranial pressure (ICP). Medical management including osmotic therapy, nimodipine, corticosteroids, and phenytoin was unable to control ICP. Intractable elevated ICP led to evacuation of the right-sided ICH. After 3.5 years, the patient appears to be cognitively intact but continues to have right lower extremity weakness and is wheelchair-bound. Our case suggests that PPCA can rarely manifest as a life-threatening emergency for which neurosurgical intervention may be life-saving.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow