Neurology India
Open access journal indexed with Index Medicus
  Users online: 64  
 Home | Login 
  About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe Etcetera Contact  
  Navigate Here 
 Search
 
  
 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (744 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed1147    
    Printed29    
    Emailed0    
    PDF Downloaded18    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 


 
Table of Contents    
LETTER TO EDITOR
Year : 2011  |  Volume : 59  |  Issue : 6  |  Page : 917-918

Role of endovascular embolisation in treatment of pediatric dural arteriovenous fistula: A case report with a review of the literature


Department of Radiology and Imaging Sciences, Sri Ramachandra University, Chennai - 600 116, India

Date of Submission28-Apr-2011
Date of Decision28-Apr-2011
Date of Acceptance09-Jul-2011
Date of Web Publication2-Jan-2012

Correspondence Address:
Lakshmi Sudha Prasanna Karanam
Department of Radiology and Imaging Sciences, Sri Ramachandra University, Chennai - 600 116
India
Login to access the Email id


DOI: 10.4103/0028-3886.91385

Get Permissions



How to cite this article:
Prasanna Karanam LS, Baddam SR, Joseph S. Role of endovascular embolisation in treatment of pediatric dural arteriovenous fistula: A case report with a review of the literature. Neurol India 2011;59:917-8

How to cite this URL:
Prasanna Karanam LS, Baddam SR, Joseph S. Role of endovascular embolisation in treatment of pediatric dural arteriovenous fistula: A case report with a review of the literature. Neurol India [serial online] 2011 [cited 2014 Oct 30];59:917-8. Available from: http://www.neurologyindia.com/text.asp?2011/59/6/917/91385


Sir,

Dural arteriovenous fistulae (DAVF) account for 10-15% of all intracranial arteriovenous malformations and are rare in the pediatric population with a reported incidence of 10%. [1],[2],[3] We describe DAVF in an eight-month-old treated by endovascular embolisation with significant clinical improvement.

An eight-month-old male child presented with breathlessness, generalized tonic clonic seizures, and delayed milestones. On clinical examination he had signs of respiratory distress, cardiac murmur and facial nevus with dilated veins, bruit predominantly in the right frontal region [Figure 1]. Two-dimensional (2D) echocardiogram revealed isolated right pulmonary vein with drainage into inominate vein and dilated cardiac chambers. Chest radiograph [Figure 2] showed cardiomegaly and widened superior mediastinum. Computed tomogram (CT) of brain revealed dilated ventricular system with avidly enhancing extra-axial lesion in the occipital region. Digital subtraction angiogram (DSA) confirmed the presence of DAVF in the posterior part of the superior sagittal sinus fed by feeders from bilateral occipital, middle meningeal, and superficial temporal arteries with transosseous feeders, pial branches from the left posterior cerebral artery, meningeal branches from internal carotid arteries, leading to a large dilated venous sac situated in the posterior part of the superior sagittal sinus and drains through both transverse, sigmoid and jugular systems [Figure 3]a-d. There was presence of cortical venous reflux. However, the jugular bulbs were normal. Subsequently, the child was taken up for embolisation, 4F slip catheter was placed in the left middle meningeal artery and feeders were selectively catheterized and embolised with 60% N-butyl cyanoacrylate glue. Similar procedure was done on the right middle meningeal artery. Then the right occipital artery was selectively catheterized with Marathon/Mirage microcatheter/microwire combination and onyx 18 (0.4cc) was injected. Post-procedure angiogram revealed near total obliteration of all the embolised feeders with significant reduction in the shunt, more than 90% [Figure 4]a-d. The venous drainage was predominantly antegrade. Immediate followup showed that the dilated veins over the right frontal region with bruit had completely subsided and child was relived of respiratory distress. At three months, six months, and one year follow-up there was significant improvement in the child's clinical status with seizures and cardiac function being well controlled.
Figure 1: Clinical photograph of the child showing facial nevus with dilated scalp veins on right frontal region

Click here to view
Figure 2: Chest X-ray showing cardiomegaly and widened superior mediastinum

Click here to view
Figure 3: (a) Left external carotid angiogram showing dural fistula at the posterior portion of the superior sagittal sinus with multiple feeders from the left middle meningeal artery; (b) Multiple feeders from the right middle meningeal artery to the fistula; (c) Feeders from the meningeal branches of the right internal carotid artery; (d) Feeders from the right occipital artery. Fistula is draining into the dilated posterior part of the superior sagittal sinus into the transverse and jugular systems

Click here to view
Figure 4: (a) Selective catheterization of left middle meningeal artery with Marathon/mirage wire combination; (b) Post-embolisation angiogram showing occlusion of the feeders of the left middle meningeal artery; (c) Post-embolisation angiogram of right middle meningeal artery shows significant reduction of the flow through the fistula; (d) Post-embolisation angiogram of right occipital artery with ONYX resulted in near total occlusion of fistula

Click here to view


In children DAVF usually tend to be multifocal and more aggressive as compared to adults. [5] Our present case had a dural sinus malformation. Three types of dural arteriovenous shunts have been described in the pediatric population: (1) neonatal type dural AV shunt, a malformation of dural sinus (DSM), (2) infantile dural arteriovenous shunt, and (3) adult type DAVF. [5] DSM are associated with slow-flow multiple AV shunts within the wall of the dural pouch contributing to venous congestion. The most common symptoms are related to increased intracranial pressure, cardiac failure and coagulation disorders. Infantile shunts usually are multifocal and present with congestive cardiac failure. The natural history includes progressive venous occlusion usually present with well-tolerated congestive heart failure. Treatment is postponed until the development of macrocrania. Cavernous sinus capture determines the development of neurological symptoms which is the natural bypass to the venous outflow. [5,6] Lasjunuias et al., suggested that a primary underlying structural weakness of the dura coincides with a trigger factor resulting in the formation of DAVF. [7]

Endovascular treatment of DAVF is lifesaving in the setting of cardiac failure as in our patient. Targeted embolisation at the specific area of shunting should be aimed as proximal embolisation is associated with rate of recurrence. [8]

 
  References Top

1.Souza MP, Urllinsky RA, Ter Brugge KG. Intracranial dural arteriovenous shunts in children: The Toronto experience. Interv Neuroradiol 2003;9(Suppl 2):47-52.  Back to cited text no. 1
    
2.Yau CK, Alvarez H, Lasjunias P. Dural sinus malformation with dural arteriovenous fistula. Interv Neuroradiol 2001;7:319-23.  Back to cited text no. 2
    
3.Lasjunias P, Magufis A. Anatomoclinical aspects of dural arteriovenous shunts in children. Interv Neuroradiol 1996;2:179-91.  Back to cited text no. 3
    
4.Lasjaunias PL, Magufis A, Goulao A, Piske R, Suthipongchai S, Rodesch R, et al. Anatomoclinical aspects of dural arteriovenous shunts in children. Interv Neuroradiol 1996,2:179-91.  Back to cited text no. 4
    
5.Lasjaunias PL, terBrugge K. Vascular diseases in neonates: Infants and Children: Interventional Neuro-radiology Management. In: Lasjaunias PL, editor. Paris: Springer-Verlag Berlin Heidelberg; 1997.  Back to cited text no. 5
    
6.Vilela P, Willinsky R, Terbrugge K. Treatment of intracranial venous occlusive disease with sigmoid sinus angioplasty and stent placement in a case of infantile multifocal dural arteriovenous shunts. Interv Neuroradiol 2001;7:51-60.  Back to cited text no. 6
[PUBMED]    
7.Awad IA, Barrow DL. Dural arteriovenous malformations. 2 nd ed. Illinois, USA: American Association of Neurological Surgeons Publications; 1993.  Back to cited text no. 7
    
8.Kincaid PK, Duckwiler GR, Gobin YP, Viñuela F. Dural Arteriovenous fistula in children: Endovascular treatment and outcomes in seven cases. AJNR Am J Neuroradiol 2001,22:1217-25.  Back to cited text no. 8
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]

This article has been cited by
1 The Molecular Pathology of Primary Brain Tumors
David S. Hersh,Rupal I. Mehta,Graeme F. Woodworth,Rudy J. Castellani
Pathology Case Reviews. 2013; 18(5): 210
[Pubmed]



 

Top
Print this article  Email this article
   
Online since 20th March '04
Published by Medknow