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Table of Contents    
CORRESPONDENCE
Year : 2011  |  Volume : 59  |  Issue : 6  |  Page : 946

Authors' reply


Department of Neurology, China-Japan Union Hospital, Jilin University, Jilin, China

Date of Submission10-Nov-2011
Date of Decision10-Nov-2011
Date of Acceptance21-Nov-2011
Date of Web Publication2-Jan-2012

Correspondence Address:
Zhaoshi Zheng
Department of Neurology, China-Japan Union Hospital, Jilin University, Jilin
China
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How to cite this article:
Zheng Z, Han X, Chang Y, Liu S. Authors' reply. Neurol India 2011;59:946

How to cite this URL:
Zheng Z, Han X, Chang Y, Liu S. Authors' reply. Neurol India [serial online] 2011 [cited 2014 Jul 28];59:946. Available from: http://www.neurologyindia.com/text.asp?2011/59/6/946/91402


Sir,

thank Dr. Lohiya [1] for raising some pertinent points regarding our article. [2] Dr. Lohiya feels that the patient we reported had viral encephalitis and associated rhabdomyolysis secondary to viral infection. We have done multiple blood tests to exclude viral infections. Rhabdomyolysis in our patient was probably related to the use of statins in "special breakfast for keeping fit". There was an obvious temporal relation between the use of statins and the encephalopathy. However, we had not emphasized this aspect in the paper. The author points to the discordance between the rapid improvement in neurological symptoms and persistent CPK rise. This discordance may be related to the mechanism of cerebral involvement in rhabdomyolysis as discussed in the article. We believe that the neurological symptoms are a non-specific response to systemic inflammatory response which occurs in patients with widespread rhabdomyolysis. This process may settle much earlier than the fall in the CPK levels.

 
  References Top

1.Lohiya RV. Encephalopathy as an initial symptom of rhabdomyolysis. Neurol India 2011 59:946.  Back to cited text no. 1
  Medknow Journal  
2.Z, Han X, Chang Y, Liu S. "Encephalopathy as an initial symptom of rhabdomyolysis". Neurol India 2011;59:764-6.  Back to cited text no. 2
    




 

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