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| CORRESPONDENCE |
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| Year : 2011 | Volume
: 59
| Issue : 6 | Page : 946 |
Authors' reply
Zhaoshi Zheng, Xuemei Han, Yin Chang, Songyan Liu
Department of Neurology, China-Japan Union Hospital, Jilin University, Jilin, China
| Date of Submission | 10-Nov-2011 |
| Date of Decision | 10-Nov-2011 |
| Date of Acceptance | 21-Nov-2011 |
| Date of Web Publication | 2-Jan-2012 |
Correspondence Address: Zhaoshi Zheng Department of Neurology, China-Japan Union Hospital, Jilin University, Jilin China

How to cite this article: Zheng Z, Han X, Chang Y, Liu S. Authors' reply. Neurol India 2011;59:946 |
Sir,
thank Dr. Lohiya [1] for raising some pertinent points regarding our article. [2] Dr. Lohiya feels that the patient we reported had viral encephalitis and associated rhabdomyolysis secondary to viral infection. We have done multiple blood tests to exclude viral infections. Rhabdomyolysis in our patient was probably related to the use of statins in "special breakfast for keeping fit". There was an obvious temporal relation between the use of statins and the encephalopathy. However, we had not emphasized this aspect in the paper. The author points to the discordance between the rapid improvement in neurological symptoms and persistent CPK rise. This discordance may be related to the mechanism of cerebral involvement in rhabdomyolysis as discussed in the article. We believe that the neurological symptoms are a non-specific response to systemic inflammatory response which occurs in patients with widespread rhabdomyolysis. This process may settle much earlier than the fall in the CPK levels.
| » References | |  |
| 1. | Lohiya RV. Encephalopathy as an initial symptom of rhabdomyolysis. Neurol India 2011 59:946.  |
| 2. | Z, Han X, Chang Y, Liu S. "Encephalopathy as an initial symptom of rhabdomyolysis". Neurol India 2011;59:764-6.  |
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