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 ORIGINAL ARTICLE
Year : 2012  |  Volume : 60  |  Issue : 3  |  Page : 288--293

Trends in clinical features and early outcome in patients with acute cardioembolic stroke subtype over a 19-year period


1 Cerebrovascular Division, Department of Neurology, Capio Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona; CIBER de Enfermedades Respiratorias (CB06/06), Instituto de Salud Carlos III, Madrid, Spain
2 Cerebrovascular Division, Department of Neurology, Capio Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain
3 Clinical Information Systems, Hospital Germans Trias i Pujo, Badalona, Barcelona, Spain
4 CIBER de Enfermedades Respiratorias (CB06/06), Instituto de Salud Carlos III, Madrid; Service of Pneumology, Capio Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain

Correspondence Address:
Adrià Arboix
Department of Neurology, Cerebrovascular Division, Capio Hospital Universitari del Sagrat Cor, Viladomat 288, E-08029 Barcelona
Spain
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.98513

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Objectives: To assess changing trends in clinical characteristics and early outcome of patients with acute cardioembolic stroke (ACS) over a 19-year period. Materials and Methods: Data of 575 patients with first-ever ACS included in the Sagrat Cor Hospital of Barcelona Stroke Registry were analyzed. Changing trends for 1986-1992, 1993-1998, and 1999-2004 periods were compared. Results: A statistically significant increase (P < 0.001) in the age of patients (74.6 years in 1986-1992 vs. 81.4 years in 1999-2004) and the percentage of patients older than 85 years of age (16% vs. 38.2%) was observed. Patients with hypertension increased from 40.5 to 60.8% (P = 0.001) as were patients with diabetes, chronic bronchitis, and obesity (P = NS). The median length of hospital stay decreased from 18 to 12 days (P = 0.031) and prolonged hospital stay (>12 days) from 18.3 to 13.1 (P = 0.033). In-hospital death rate remained around 20%. Conclusions: ACS continues to be a severe ischemic stroke subtype with high risk of in-hospital death. The lack of improvement in the early prognosis over a 19-year period may be explained by an increase in the prevalence of major cardiovascular risk factors and progressive aging of the population.






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