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Table of Contents    
LETTER TO EDITOR
Year : 2012  |  Volume : 60  |  Issue : 3  |  Page : 368

Clinical and polysomnographic characteristics in 20 north Indian patients with narcolepsy: A seven-year experience from a neurology service


1 Department of Neurology, Mevki Military Hospital, Ankara, Turkey
2 Department of Neurology, Kasimpasa Military Hospital, Istanbul, Turkey
3 Department of Neurology, GATA, Haydarpa?a Training Hospital, Istanbul, Turkey

Date of Submission12-Apr-2012
Date of Decision12-Apr-2012
Date of Acceptance10-Jun-2012
Date of Web Publication14-Jul-2012

Correspondence Address:
Senol Mehmet Güney
Department of Neurology, GATA, Haydarpa?a Training Hospital, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.98550

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How to cite this article:
Halit Y, Hakan T, Güney SM. Clinical and polysomnographic characteristics in 20 north Indian patients with narcolepsy: A seven-year experience from a neurology service. Neurol India 2012;60:368

How to cite this URL:
Halit Y, Hakan T, Güney SM. Clinical and polysomnographic characteristics in 20 north Indian patients with narcolepsy: A seven-year experience from a neurology service. Neurol India [serial online] 2012 [cited 2019 Aug 22];60:368. Available from: http://www.neurologyindia.com/text.asp?2012/60/3/368/98550


Sir,

We read with great interest the article by Gupta et al. [1] However, we would like to discuss some issues of the study. In this study, polysomnography recordings of leg movements were recorded only from the right leg. Unfortunately, this would cause periodic leg movement (PLM) index to be lower. American Academy of Sleep Medicine (AASM) recommends scientists to record leg movements from both tibialis anterior muscles. [2] Also, in the article, there is no information about the PLM index. But in patients with narcolepsy, especially the ones with cataplexy, PML syndrome may coexist and this could contribute to the increase of arousal index. [3] Studies show that the prevalence of narcolepsy within the first-degree relatives of narcolepsy patients is high. [4] For this reason, the first-degree relatives of narcolepsy patients are also recommended to be scanned for narcolepsy. Hypocretin-1 level in the cerebrospinal fluid (CSF) is one of the diagnostic criteria for narcolepsy. Its level is recommended as determining the diagnostic criteria, especially in narcolepsy patients with cataplexy and in patients who have multiple sleep latency test (MSLT) difficult to interpret. [5]

 
 » References Top

1.Gupta A, Shukla G, Goyal V, Srivastava A, Behari M. Clinical and polysomnographic characteristics in 20 North Indian patients with narcolepsy: A seven-year experience from a neurology service sleep clinic. Neurol India 2012;60:75-8.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. American Academy of Sleep Medicine, 2007.  Back to cited text no. 2
    
3.Plazzi G, Ferri R, Franceschini C, Vandi S, Detto S, Pizza F, et al. Periodic leg movements during sleep in narcoleptic patients with or without restless legs syndrome. J Sleep Res 2012;21:155-62.  Back to cited text no. 3
[PUBMED]    
4.Wing YK, Chen L, Lam SP, Li AM, Tang NL, Ng MH, et al. Familial aggregation of narcolepsy. Sleep Med 2011;12:947-51.  Back to cited text no. 4
[PUBMED]  [FULLTEXT]  
5.Mignot E, Lammers GJ, Ripley B, Okun M, Nevsimalova S, Overeem S, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002;59:1553-62.  Back to cited text no. 5
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Gupta, A. and Shukla, G. and Goyal, V. and Srivastava, A. and Behari, M.
Neurology India. 2012; 60(3): 368-369
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