Atormac
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 2090  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 Search
 
  
 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (642 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed1434    
    Printed35    
    Emailed0    
    PDF Downloaded31    
    Comments [Add]    

Recommend this journal

 


 
Table of Contents    
LETTER TO EDITOR
Year : 2013  |  Volume : 61  |  Issue : 6  |  Page : 686-687

Primary leiomyoma of the parietal bone


1 Department of Neurosurgery, The First People's Hospital of Neijiang, Neijiang 641000, Sichuan, China
2 Department of Pathology, The First People's Hospital of Neijiang, Neijiang 641000, Sichuan, China

Date of Submission23-Oct-2013
Date of Decision28-Oct-2013
Date of Acceptance04-Dec-2013
Date of Web Publication20-Jan-2014

Correspondence Address:
Cong Liu
Department of Neurosurgery, The First People's Hospital of Neijiang, Neijiang 641000, Sichuan
China
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.125384

Rights and Permissions



How to cite this article:
Wu Q, Liu C, Luo X, Fan Y, Zhou L, Liu Q. Primary leiomyoma of the parietal bone. Neurol India 2013;61:686-7

How to cite this URL:
Wu Q, Liu C, Luo X, Fan Y, Zhou L, Liu Q. Primary leiomyoma of the parietal bone. Neurol India [serial online] 2013 [cited 2019 Nov 15];61:686-7. Available from: http://www.neurologyindia.com/text.asp?2013/61/6/686/125384


Sir,

A 14-year-old boy presented with a 3-month history of progressive enlargement over the right parietal bone. On examination, a 2.0 cm × 1.5 cm sized, hard, fixed mass over the right parietal bone was found. Computerized tomography (CT) revealed a 1.6 cm × 1.0 cm isodense mass with partial erosion of the outer table of the right parietal bone [Figure 1]a. Total resection of the mass was performed under local anesthesia. The mass was hard, hypovascular and capsulated with kind of faint yellow membrane and it eroded the whole of skull while leaving the dura untouched. The specimen mainly contained spindle cells positive for vimentin and smooth muscle actin (SMA) [Figure 1]b while negative for epithelial membrane antigen, S-100, CD34 and Bcl-2 on immunohistochemistry staining, which was consistent with leiomyoma. The post-operative course was uneventful. Three months after the surgery, CT [Figure 1]c showed no evidence of local recurrence.
Figure 1: (a) Computerized tomography (CT) revealed an isodense mass with partial erosion of the outer table of the right parietal bone (b) strong immunoreactivity for smooth muscle actin (×100) (c) follow-up CT showed no evidence of local recurrence

Click here to view


Leiomyomas are benign well-differential smooth-muscle tumors, and are characterized by positive immunoreactivity of SMA and vimentin. [1],[2] They commonly arise in uterus, gastrointestinal and urinary tracts, skin and mucous membranes. They may develop wherever the smooth muscle is present. However, it rarely occurs in the bone. Several cases of leiomyoma arising in the bone have been reported. [2] To the best of our knowledge, only one case of leiomyoma of skull vault has been reported in recent English language literatures. [1] Leiomyoma of the uterus is the most common, whereas leiomyoma of bone has been very rarely reported, which may be probably due to the paucity of smooth muscle in the bone. Enzinger and Weiss reported that 95% of 7748 leiomyomas occurred in the uterus, 3% in the skin, 0.9% in the gastrointestinal tract and the remainder distributing at other sites. The main clinical manifestation of intraosseous leiomyoma is nonspecific pain. [2] Our patient presented with painless progressive enlargement of the mass. Although leiomyoma is a benign tumor, it can metastasize to many sites of the body such as lung, skull base and spine. [3],[4] On the CT and magnetic resonance imaging images the leiomyoma appears to be well-defined, isodense and homogeneous. [1],[5] Leiomyoma of the skull should be differentiated from Langerhans' cell histiocytosis, fibrous dysplasia and infantile myofibromatosis. [6] Surgery is considered to be the first choice of the treatment for leiomyoma and long-term follow-up is strongly commended.

 
  References Top

1.Jeung CU, Song SH, Kim SH, Song KS. Primary leiomyoma of the temporal bone. J Korean Neurosurg Soc 2004;35:321-3.  Back to cited text no. 1
    
2.Laffosse JM, Gomez-Brouchet A, Giordano G, Bonnevialle N, Puget J. Intraosseous leiomyoma: A report of two cases. Joint Bone Spine 2007;74:389-92.  Back to cited text no. 2
[PUBMED]    
3.Alessi G, Lemmerling M, Vereecken L, De Waele L. Benign metastasizing leiomyoma to skull base and spine: A report of two cases. Clin Neurol Neurosurg 2003;105:170-4.  Back to cited text no. 3
[PUBMED]    
4.Clichy F. Leiomyomatosis metastasizing to the spine. J Bone Joint Surg 1983;65-A:1163.  Back to cited text no. 4
    
5.Yang BT, Wang ZC, Xian JF, Hao DP, Chen QH. Leiomyoma of the sinonasal cavity: CT and MRI findings. Clin Radiol 2009;64:1203-9.  Back to cited text no. 5
[PUBMED]    
6.Behar PM, Albritton FD, Muller S, Todd NW. Multicentric infantile myofibromatosis. Int J Pediatr Otorhinolaryngol 1998;45:249-54.  Back to cited text no. 6
[PUBMED]    


    Figures

  [Figure 1]



 

Top
Print this article  Email this article
   
Online since 20th March '04
Published by Wolters Kluwer - Medknow