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Table of Contents    
AUTHORS REPLY
Year : 2013  |  Volume : 61  |  Issue : 6  |  Page : 703

Authors reply


1 Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Date of Web Publication20-Jan-2014

Correspondence Address:
Satyawati Mohindra
Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh
India
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Mohindra S, Mohindra S, Gupta K. Authors reply. Neurol India 2013;61:703

How to cite this URL:
Mohindra S, Mohindra S, Gupta K. Authors reply. Neurol India [serial online] 2013 [cited 2019 Sep 18];61:703. Available from: http://www.neurologyindia.com/text.asp?2013/61/6/703/125426


Sir

First of all we would like to thank Erkan et al.,[1] for reading our paper in detail. We have gone through their comments carefully. [2] In our study, [3] we have mentioned about their article in relation to histopathological changes which took place after application of fibrin glue. Though our study was based on pediatric population, nowhere we have mentioned that these changes were observed in human beings. Observation of these changes in human beings are difficult due to ethical considerations. In our department, [3],[4] we have been performing endoscopic closure of cerebrospinal fluid rhinorrhea with and without fibrin glue for the past many years and we have not observed any such adverse reactions like mucosal damage, increased mucosal thickness, decreased perichondrial thickness and cartilaginous thickness, and segmental cartilage loss. In our study, the rate of recurrent csf rhinorrhea in patients where fibrin glue was used, was marginally more than the non-glue group but the results were not statistically significant. As far as mentioning your article in relation to csf rhinorrhea is concerned, we do regret that, but we would like to draw your attention to your article where in introduction (first paragraph) you have mentioned the use of fibrin glue for various surgeries including csf rhinorrhea. The source of this observation has not been mentioned. Admittedly, we have presented a small series of patients and a larger series of patients and a systematically planned case-control study is required to definitely address the questions which are still remaining.

 
  References Top

1.Erkan AN, Cakmak O, Kocer NE, Yýlmaz I. Effects of fibrin glue on nasal septal tissues. Laryngoscope 2007;117:491-6.  Back to cited text no. 1
    
2.Erkan AN. Comment on "Susceptibility-weighted imaging: The value in cerebral astrocytomas" Neurol India 2014 [In this issue].  Back to cited text no. 2
    
3.Mohindra S, Mohindra S, Gupta K. Endoscopic repair of CSF rhinorrhea: Necessity of fibrin glue. Neurol India 2013;61:396-9.  Back to cited text no. 3
[PUBMED]  Medknow Journal  
4.Yadav JS, Mohindra S, Francis AA. CSF rhinorrhea-feasibility of conservative management in children. Int J Pediatr Otorhinolaryngol 2011;75:186-9.  Back to cited text no. 4
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