Atormac
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 7818  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 Search
 
  
 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (366 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed1606    
    Printed31    
    Emailed0    
    PDF Downloaded63    
    Comments [Add]    
    Cited by others 2    

Recommend this journal

 


 
Table of Contents    
NEUROIMAGE
Year : 2014  |  Volume : 62  |  Issue : 1  |  Page : 113-114

Dumbbell shaped spinal hydatidosis


Department of Neurosurgery, M. S. Ramaiah Institute of Neurosciences, Bengaluru, Karnataka, India

Date of Web Publication7-Mar-2014

Correspondence Address:
Krishna Chaitanya Joshi
Department of Neurosurgery, M. S. Ramaiah Institute of Neurosciences, MSRIT Post, New BEL Road, Bengaluru, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.128363

Rights and Permissions



How to cite this article:
Joshi KC, Jagannath AT, Varma RG. Dumbbell shaped spinal hydatidosis. Neurol India 2014;62:113-4

How to cite this URL:
Joshi KC, Jagannath AT, Varma RG. Dumbbell shaped spinal hydatidosis. Neurol India [serial online] 2014 [cited 2019 Nov 14];62:113-4. Available from: http://www.neurologyindia.com/text.asp?2014/62/1/113/128363


Sir,

A 28-year-old male patient from Iraq presented with progressively increasing pain on the left side of chest since past 2 months and weakness of lower limbs since 2 weeks. Neurological examination revealed spastic paraparesis with motor power of 4/5. Local examination of spine revealed tenderness over the spinous process of T5 and T6 vertebrae. Chest X-ray revealed homogenous mediastinal opacity on the left side at the level of T5-6 and erosion of the head of left fifth rib. Contrast enhanced magnetic resonance imaging revealed 4 × 5 cm cystic lesion in the posterior mediastinum left paravertebral region with extension into the spinal canal through T5-6 foramen. The intra spinal extradural part had multiple septations and had a contrast enhancing cyst wall [Figure 1]. He underwent T5-6 laminectomy and at operation there were multiple cysts in the extradural space with a large cyst extending into the posterior mediastinum on the left side. The cavity was irrigated with 3 % hypertonic saline. During resection of the pericyst we encountered a small breech in the parietal pleura, which was sutured. The histopathological examination of cysts revealed them to be Echinoccous granulosus.
Figure 1: DRIVE (3D-T2W-driven equilibrium radiofrequency reset pulse) and 3D T1 reformatted right (a and c) and left (b and d) sagittal oblique images reveals normal right trigeminal nerve (thin arrow) with nonvisualization of left trigeminal nerve (long thick arrow). Tortuous left vertebral artery is displacing the severely atrophic left trigeminal nerve (short thick arrows) on 3D fl uid attenuated inversion recovery image (e)

Click here to view


Hydatid disease is caused by the larval stage of the cestode, E. Granulosus and is highly prevalent in countries with temperate climates. [1] The lifecycle of E. granulosus involves two hosts. The definitive host is a dog or other related carnivore where the adult parasite lodges in the proximal small bowel and the eggs are shed in the feces. The intermediate host, usually a sheep (or some other herbivore), gets infected when grazing on contaminated ground. The embryo (oncosphere) hatches, penetrates the intestinal mucosa, develops into the characteristic vesicular metacestode on reaching a suitable anatomical site. When the definitive host feeds on infected viscera, the cycle is complete. [2] Humans are accidental hosts.

Spinal hydatidosis, involvement of the spinal cord, the spine, or both structures, is associated with a high degree of morbidity and mortality and the prognosis has often been compared with that of malignancies. [3],[4],[5] Extra-visceral hydatid disease is generally thought to evolve from arterial dissemination of the oncospheres and the other proposed route is venous, through porto-vertebral shunts and the retrograde passage of the parasite from the inferior vena cava to retroperitoneal and epidural venous plexuses. [6] Mediastinal hydatid cyst with intraspinal extension is an extremely rare entity, less than ten cases have been reported until date. [7] Extension of the lesion through the spinal canal gives them the unique dumbbell shape.[8] The differential diagnosis of dumbbell lesion include benign/malignant peripheral nerve sheath tumors, plasmacytoma, chondrosarcoma, chondroid chordoma, superior sulcus tumor, metastasis and non-neoplastic lesions such as infectious process (tuberculosis, hydatid cyst), aneurysmal bone cyst, synovial cyst, traumatic pseudomeningocele, arachnoid cyst and hemangiomas. Mediastinal hydatid cysts with intra spinal extensions can lead to destruction of the vertebral body and the adjacent rib. Braithwaite and Lees [9] have anatomically classified spinal hydatidosis into five categories: Type 1 - intramedullary, type 2 - intradural extramedullary, type 3 - extradural intraspinal, type 4 - vertebral and type 5 - paravertebral or dumbbell shaped.

Mediastinal hydatid should always be considered in the differential diagnosis of cystic lesions with intra spinal extension, especially in endemic areas and serological testing should be considered pre-operatively. The best treatment for spinal hydatidosis is surgical excision of the germinative membrane and pericyst. Pre-operative treatment with benzimidazoles has been reported to soften the cysts and to reduce intracystic pressure, enabling the surgeon to remove the endocyst more easily. It is recommended for cases in which spillage of protoscoleces may have occurred during surgery to initiate post-operative chemotherapy with albendazole (ABZ) or mebendazole (MBZ) immediately after the operation for at least 1 month (ABZ) or 3 months (MBZ). [10]

 
  References Top

1.Grosso G, Gruttadauria S, Biondi A, Marventano S, Mistretta A. Worldwide epidemiology of liver hydatidosis including the Mediterranean area. World J Gastroenterol 2012;18:1425-37.  Back to cited text no. 1
    
2.Schantz PM, PB, E. In: Guerrant RL, DH, Weller PF, editors. Echinococcosis. 2 nd ed. Philadelphia: Churchill Livingstone (Elsevier); 2006.  Back to cited text no. 2
    
3.Kammerer WS. Echinococcosis affecting the central nervous system. Semin Neurol 1993;13:144-7.  Back to cited text no. 3
    
4.Ozdemir HM, Ogün TC, Tasbas B. A lasting solution is hard to achieve in primary hydatid disease of the spine: Long-term results and an overview. Spine (Phila Pa 1976) 2004;29:932-7.  Back to cited text no. 4
    
5.Pedrosa I, Saíz A, Arrazola J, Ferreirós J, Pedrosa CS. Hydatid disease: Radiologic and pathologic features and complications. Radiographics 2000;20:795-817.  Back to cited text no. 5
    
6.Pamir MN, Ozduman K, Elmaci I. Spinal hydatid disease. Spinal Cord 2002;40:153-60.  Back to cited text no. 6
    
7.Ranganadham P, Dinakar I, Sundaram C, Ratnakar KS, Vivekananda T. Posterior mediastinal paravertebral hydatid cyst presenting as spinal compression. A case report. Clin Neurol Neurosurg 1990;92:149-51.  Back to cited text no. 7
    
8.Kilic D, Erdogan B, Sener L, Sahin E, Caner H, Hatipoglu A. Unusual dumbbell tumours of the mediastinum and thoracic spine. J Clin Neurosci 2006;13:958-62.  Back to cited text no. 8
    
9.Braithwaite PA, Lees RF. Vertebral hydatid disease: Radiological assessment. Radiology 1981;140:763-6.  Back to cited text no. 9
    
10.Paw³owski ZS, Eckert J, Vuitton DA, Ammann RW, Kern P, Craig PS, et al . Echinococcosis in humans: Clinical aspects, diagnosis and treatment. In: Eckert J, Johannes Eckert, Meslin F-X, Paw³owsk ZS, editors. Paris: World Organisation for Animal Health (Office International des Epizooties) and World Health Organization; 2001.  Back to cited text no. 10
    


    Figures

  [Figure 1]

This article has been cited by
1 Dumbell hydatid disease of spine with posterior paraspinal muscle involvement
Ranjeet Ramesh Jagadale,Kanicka Yashi,Reddy V. Umamaheswara,Amit Agrawal
Romanian Neurosurgery. 2015; 29(3)
[Pubmed] | [DOI]
2 A large primary dumbbell hydatid cyst causing neural foraminal widening of the thoracic spine: A case report and literature review
Ahmet Karakasli,Murat Yilmaz,Ali Osman Mucuoglu,Alaattin Yurt
International Journal of Surgery Case Reports. 2015; 8: 55
[Pubmed] | [DOI]



 

Top
Print this article  Email this article
   
Online since 20th March '04
Published by Wolters Kluwer - Medknow