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Table of Contents    
CORRESPONDENCE
Year : 2015  |  Volume : 63  |  Issue : 2  |  Page : 291

Approach to diagnosis and management of optic neuropathy due to copper deficiency


Neuro-Ophthalmology Clinic and Glaucoma Service, AG Eye Hospital, Puthur, Trichy, Tamil Nadu, India

Date of Web Publication5-May-2015

Correspondence Address:
Nataraja Pillai Venugopal
Neuro-Ophthalmology Clinic and Glaucoma Service, AG Eye Hospital, Puthur, Trichy, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.156324

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How to cite this article:
Venugopal NP. Approach to diagnosis and management of optic neuropathy due to copper deficiency. Neurol India 2015;63:291

How to cite this URL:
Venugopal NP. Approach to diagnosis and management of optic neuropathy due to copper deficiency. Neurol India [serial online] 2015 [cited 2019 Oct 21];63:291. Available from: http://www.neurologyindia.com/text.asp?2015/63/2/291/156324


Sir,

We read with interest the review article titled "Approach to diagnosis and management of optic neuropathy" [1] by Mustafa and Pandit. We appreciate the authors' effort and research work. We would like to highlight a few points regarding copper deficiency. There are a few case reports of optic neuropathy in patients with low copper level, [2] presenting with reduced visual acuity and color vision, constricted visual fields, optic atrophy, and thinning of retinal nerve fibers. Scotopic and photopic electroretinograms were normal suggesting that the retinal function was normal. Copper deficiency is a rare cause for progressive optic neuropathy and myelopathy [3],[4],[5] and hence should be considered in the differential diagnosis. It is crucial to elicit a history of gastric surgery or other risk factors for hypocupremia in patients undergoing evaluation for subacute or chronically progressive optic neuropathy or myelopathy.

 
  References Top

1.
Mustafa S, Pandit L. Approach to diagnosis and management of optic neuropathy. Neurol India 2014;62:599-605.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Ugarte M, Osborne NN, Brown LA, Bishop PN. Iron, zinc, and copper in retinal physiology and disease. Surv Ophthalmol 2013;58:585-609.  Back to cited text no. 2
    
3.
Pineles SL, Wilson CA, Balcer LJ, Slater R, Galetta SL. Combined optic neuropathy and myelopathy secondary to copper deficiency. Surv Ophthalmol 2010;55:386-92.  Back to cited text no. 3
    
4.
Sharma C, Nath K, Kumawat BL, Khandelwal D, Jain D. Erb's paraplegia with primary optic atrophy: Unusual presentation of neurosyphilis: Case report and review of literature. Ann Indian Acad Neurol 2014;17:231-3.  Back to cited text no. 4
[PUBMED]  Medknow Journal  
5.
Narayan SK, Kaveer N. CNS demyelination due to hypocupremia in Wilson's disease from overzealous treatment. Neurol India 2006;54:110-1.  Back to cited text no. 5
[PUBMED]  Medknow Journal  




 

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