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NEUROIMAGES
Year : 2016  |  Volume : 64  |  Issue : 3  |  Page : 576-577

A rare case of adult tapeworm in the brain


1 Department of Neurosurgery, Andhra Medical College, King George Hospital, Visakhapatnam, Andhra Pradesh, India
2 Department of Pathology, Gayathri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, Andhra Pradesh, India

Date of Web Publication3-May-2016

Correspondence Address:
Dr. Daya Bharath Singh Naik Banavathu
Department of Neurosurgery, Andhra Medical College, King George Hospital, Visakhapatnam - 530 002, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.181576

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How to cite this article:
Banavathu DB, Talari S, Veluri SV, Balda V. A rare case of adult tapeworm in the brain. Neurol India 2016;64:576-7

How to cite this URL:
Banavathu DB, Talari S, Veluri SV, Balda V. A rare case of adult tapeworm in the brain. Neurol India [serial online] 2016 [cited 2019 Aug 18];64:576-7. Available from: http://www.neurologyindia.com/text.asp?2016/64/3/576/181576


Neurocysticercosis is a commonly encountered entity in neurological practice in developing countries. However, the presence of adult Taenia solium worm in the brain has not been previously reported. This is the first report of an adult tapeworm in the brain.

A 30-year-old male patient presented with a history of medically refractory simple partial seizures of 2 year duration. He was diagnosed as having neurocysticercosis based on imaging and was treated with antihelminthic, antiepileptic, and later antituberculous regimen with no improvement [Figure 1]a and [Figure 1]b. Repeat scans showed the lesion to be increasing in size with perilesional edema. A right parietal craniotomy followed by exploration of the granular lesion found an adult worm.
Figure 1: (a) T1 axial contrast image showing a lesion in the right parietal region with perilesional edema. (b) T1 coronal axial image showing the lesion in the right parietal region which was contrast enhancing

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The gross appearance was a long, thread-like structure, white in color with a glistening appearance [Figure 2]a and [Figure 2]b. Microscopic examination confirmed it to be an adult T. solium with scolex showing radially arranged suckers and two rows of spiny chitinous hooks and the body showing proglottids. The proglottids shows a tegument layer with hair-like microtriches. The adjacent tissue showed fibrous connective tissue cyst wall lined by mixed inflammatory infiltrate with lymphocytes, dense polymorphs, and occasional histiocytes [Figure 3]a,[Figure 3]b,[Figure 3]c.
Figure 2: (a) Specimen of worm after removal during surgery. (b) Worm placed in a sterile container and sent for histopathological examination

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Figure 3: (a) Microscopic image of the scolex of Taenia solium worm in the granulation tissue surrounded by neuroglial tissue of the brain (H and E, ×50). (b) The scolex of the worm showing two rows of chitinous hooks and suckers characteristic of Taenia solium worm (×100). (c) Microscopic image of mature proglottids of the Taenia solium worm (H and E, ×40)

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Postoperatively, antiepileptic regimen was continued and he remained symptom-free at a follow up of 2 years. Cysticercal infestation occurs either due to ingestion of infected pork or from human to human transmission through infection from fecal matter to food.[1],[2] The adult worm usually grows in the intestine by attaching to the wall with the scolex and releases gravid proglottids. The cysticerci may penetrate the intestinal wall and through the portal circulation may finally reach muscles, eyes, or brain. Five forms of neurocysticercosis have been recognized depending on the location, namely parenchymal, arachnoidal, ventricular, spinal, and mixed. The various stages of cysticerci in the brain are colloidal, granular nodular, and nodular calcified stage.

Our first differential diagnosis had been spargoniasis as it has been reported earlier.[3] Sparganosis is a parasitic infection caused by the plerocercoid larvae of diphyllobothroid tapeworms belonging to the genus Spirometra.[3] Even intraparenchymal migration has been described. However, the diagnosis of T. solium was established by the microscopic pictures of the scolex, which are different in both the species.

It is difficult to say how a cysticercus could develop into a worm in the brain. Our effort is to make the neurological community aware of the possibility of tapeworm growing in the brain; and, there was absence of response to the administration of mainline antihelminthic drugs. The need for surgery is usually to confirm the diagnosis and in the management of cases that are not responding to medical treatment.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Suh DC, Chang KH, Han MH, Lee SR, Han MC, Kim CW. Unusual MR manifestations of neurocysticercosis. Neuroradiology 1989;31:396-402.  Back to cited text no. 1
    
2.
Garcia HH, Del Brutto OH. Taenia solium cysticercosis. Infect Dis Clin North Am 2000;14:97-119, ix.  Back to cited text no. 2
    
3.
Hughes AJ, Biggs BA. Parasitic worms of the central nervous system: An Australian perspective. Intern Med J 2002;32:541-53.  Back to cited text no. 3
    


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