| ORIGINAL ARTICLE
|Year : 2016 | Volume
| Issue : 6 | Page : 1187--1192
Acute disseminated encephalomyelitis: A clinical and neuroradiological profile of pediatric patients
Prabhas Prasun Giri1, Sukanta Bhattyacharya1, Dipankar Das2, Swapan Mukhopadhaya3
1 Department of Pediatrics, Institute of Child Health, Kolkata, West Bengal, India
2 Department of Pediatric Radiology and Imaging, Institute of Child Health, Kolkata, West Bengal, India
3 Department of Pediatric Neurology, Institute of Child Health, Kolkata, West Bengal, India
Objectives: To discuss the clinical and neuroradiological profile of pediatric patients with acute disseminated encephalomyelitis (ADEM).
Design: Prospective observational study
Settings: Children with clinico-radiological diagnosis of ADEM admitted in the pediatric ward of the Institute of Child Health between July 2009 to Sepetember 2014 were included.
Materials and Methods: Clinical and neuroradiological parameters of children suffering from ADEM were noted.
Results: A total of 36 children were included in the study, among whom approximately 50% had a history of either a preceding viral infection or the administration of a vaccination; and, 92% of them presented with some form of neurological deficits. Encephalopathy was present in 92% children at the time of admission. Seizures were present in 42% of children. The cerebrospinal fluid (CSF) study was non-contributory and magnetic resonance imaging (MRI) was diagnostic in most of the cases. The lesions were usually asymmetrically placed. All of them were treated with steroids and had a good prognosis, with complete neurological recovery in 75% of the children.
Conclusion: Although it is perceived as a rare disease, ADEM is fairly common in the pediatric population, Most often, it is misdiagnosed as a meningoencephalitis. An early neuroradiological identification of the demyelinating lesions and treatment with steroid therapy leads to an excellent outcome.
Dr. Prabhas Prasun Giri
Flat C1, Anandan, 173, Sarat Ghosh Garden Road, Dhakuria, Kolkata - 700 031, West Bengal
Source of Support: None, Conflict of Interest: None
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