Atormac
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 6469  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 Search
 
  
 Resource Links
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (824 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed1225    
    Printed18    
    Emailed0    
    PDF Downloaded33    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 


 
Table of Contents    
NEUROIMAGES
Year : 2017  |  Volume : 65  |  Issue : 3  |  Page : 672-673

Carbon monoxide toxicity: A reversible damage to brain


Department of Neurology, SAIMS Medical College, SAIMS, Indore, Madhya Pradesh, India

Date of Web Publication9-May-2017

Correspondence Address:
Ayush Dubey
E-29, 45 Bungalows, T T Nagar, Bhopal, Madhya Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/neuroindia.NI_990_16

Rights and Permissions



How to cite this article:
Dubey A, Chouksey D. Carbon monoxide toxicity: A reversible damage to brain. Neurol India 2017;65:672-3

How to cite this URL:
Dubey A, Chouksey D. Carbon monoxide toxicity: A reversible damage to brain. Neurol India [serial online] 2017 [cited 2019 Aug 17];65:672-3. Available from: http://www.neurologyindia.com/text.asp?2017/65/3/672/205952


A 55-year old female patient with previously normal neurological status was found unconscious in her house one winter morning. On examination, she was drowsy, arousable with decreased attention span and no focal neurological deficits. Her arterial blood gas showed hypoxemia. She had gradual improvement in her sensorium and hypoxemia with intranasal oxygen. She provided a history of cooking food on a household stove using wood and coal in a tightly closed room, and she slept without putting off the stove. Her magnetic resonance imaging (MRI) of the brain showed bilateral symmetrical globus pallidus hyperintensities on T2 and fluid-attenuated inversion recovery (FLAIR) sequences [Figure 1]. A diagnosis of carbon monoxide toxicity was made.[1] These hyperintensities disappeared on a follow-up MRI at 2 months[Figure 2]. In a closed room, fumes of burning wood and coal produces carbon monoxide which combines with hemoglobin reversibly and replaces oxygen, leading to hypoxemia. This special situation which leads to this presentation of isolated globus pallidus involvement is not much reported.[2] The presentation of these patients can be variable ranging from slight headache and dizziness to coma. Our patient recovered in 24–48 hours with no recurrence in follow-up.[3]
Figure 1: Axial T2 FLAIR and diffusion weighted images showing bilateral symmetrical globus pallidi hyperintensities

Click here to view
Figure 2: Follow-up scan after 2 months showing resolution of the hyperintensities

Click here to view


Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Subhaschandra S, Jatishwor W, Suraj T. Isolated symmetrical bilateral basal ganglia T2 hyperintensity in carbon monoxide poisoning. Ann Indian Acad Neurol 2008;11:251-3.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Sharma P, Eesa M, Scott J. Toxic and acquired metabolic encephalopathies: MRI appearance. Am J Radiol2009;193:879-86.  Back to cited text no. 2
    
3.
Kinoshita T, Sugihara S, Matsusue E, Fujii S, Ametani M, Ogawa T. Pallidoreticular damage in acute carbon monoxide poisoning: Diffusion-weighted MR imaging findings. Am J Neuroradiol 2005;26:1845-8.  Back to cited text no. 3
[PUBMED]    


    Figures

  [Figure 1], [Figure 2]

This article has been cited by
1 Transition from intravenous to enteral ketamine for treatment of nonconvulsive status epilepticus
Michael A. Pizzi,Prasuna Kamireddi,William O. Tatum,Jerry J. Shih,Daniel A. Jackson,William D. Freeman
Journal of Intensive Care. 2017; 5(1)
[Pubmed] | [DOI]



 

Top
Print this article  Email this article
   
Online since 20th March '04
Published by Wolters Kluwer - Medknow