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 REVIEW ARTICLE
Year : 2017  |  Volume : 65  |  Issue : 7  |  Page : 71--77

From resection to ablation: A review of resective surgical options for temporal lobe epilepsy and rationale for an ablation-based approach


Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

Correspondence Address:
Ashwini Sharan
Department of Neurosurgery, Thomas Jefferson University, 909 Walnut Street, 3rd Floor, Philadelphia, Pennsylvania
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.201662

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Surgical intervention is of proven benefit in an appropriately selected subset of patients with medically refractory temporal lobe epilepsy. In these patients, a surgical cure both provides the quality of life improvement that comes from seizure freedom as well as a survival benefit. However, patients who undergo open surgical intervention may have a worsening in neurobehavioral outcomes. Laser interstitial thermal therapy (LITT) represents a minimally invasive surgical intervention that has shown promise in improving post-operative neurobehavioral outcomes. Further, the minimally invasive nature of this procedure holds the possibility to shift the significant under-penetration of surgical intervention that exists for eligible medically refractory patients. Herein, we review open surgical resection-based techniques and the clinical data to date for LITT.






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Online since 20th March '04
Published by Wolters Kluwer - Medknow