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|Year : 2018 | Volume
| Issue : 1 | Page : 268
Reversible symptoms present in a patient with Balo's concentric sclerosis
Edyta Dziadkowiak1, Mieszko Zagrajek2, Anna Zimny3, Bogusław Paradowski2
1 Department of Neurology, University Clinical Hospital, Wroclaw, Poland
2 Department of Neurology, Wroclaw Medical University, Wroclaw, Poland
3 Department of Radiology, Wroclaw Medical University, Wroclaw, Poland
|Date of Web Publication||11-Jan-2018|
Dr. Edyta Dziadkowiak
Wroclaw Medical University, 213 Street Borowska, Wroclaw – 50-556
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Dziadkowiak E, Zagrajek M, Zimny A, Paradowski B. Reversible symptoms present in a patient with Balo's concentric sclerosis. Neurol India 2018;66:268
A 43-year old woman presented with flu-like symptoms without fever, followed by bulbar palsy. Magnetic resonance imaging revealed two symmetrical, non-enhancing, T2-hyperintense, oval, frontal subcortical lesions showing an onion-skin-like pattern [Figure 1]. Cerebrospinal fluid examination showed lymphocytic pleocytosis (10/mm3) with no immunoglobulin G oligoclonal bands. Serological tests for viruses, Lyme disease, tumor markers, antinuclear antibodies, and antibodies to aquaporin-4 water channels were negative. Pattern visual evoked potential (VEP) and the analysis of electroencephalography (EEG) data were normal. Steroid therapy resolved all symptoms. Balo's concentric sclerosis is a rare variant of multiple sclerosis. Concentric lesions are probably due to a reaction to an unknown neurochemical agent.,
|Figure 1: Magnetic resonance images showing two acute, symmetrical, frontal subcortical lesions with concentric layers of demyelination and preserved myelin clearly visible on T2-weighted images (a) and diffusion weighted images [DWI] (b), with restricted diffusion on DWI (b) and hypoperfusion on perfusion-weighted images (c), which regressed markedly three months later (d)|
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Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
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Conflicts of interest
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