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|LETTERS TO EDITOR
|Year : 2018 | Volume
| Issue : 5 | Page : 1505-1506
A rare case of spontaneous thrombosis of vein of Galen malformation in a young adult diagnosed on magnetic resonance imaging and digital subtraction angiography
Anshu Mahajan, Gaurav Goel, Biplab Das, Karanjit S Narang
Department of Neurosciences, Medanta, The Medicity, Gurgaon, Haryana, India
|Date of Web Publication||17-Sep-2018|
Dr. Gaurav Goel
Department of Neurosciences, Medanta, The Medicity, Gurgaon, Haryana
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Mahajan A, Goel G, Das B, Narang KS. A rare case of spontaneous thrombosis of vein of Galen malformation in a young adult diagnosed on magnetic resonance imaging and digital subtraction angiography. Neurol India 2018;66:1505-6
|How to cite this URL:|
Mahajan A, Goel G, Das B, Narang KS. A rare case of spontaneous thrombosis of vein of Galen malformation in a young adult diagnosed on magnetic resonance imaging and digital subtraction angiography. Neurol India [serial online] 2018 [cited 2019 Feb 16];66:1505-6. Available from: http://www.neurologyindia.com/text.asp?2018/66/5/1505/241344
A 30-year old male patient presented with complaints of severe headache for 15 days not relieved by medication. He had no significant medical history. Magnetic resonance imaging (MRI) showed a hyperintense oval lesion in the quadrigeminal cistern and a curvilinear hyperintensity in the third ventricular region, which were in continuation with each other on fluid attenuated inversion recovery image and T1-weighted image [Figure 1]a-c]. MRI findings were suggestive of thrombosed vein of Galen and bilateral internal cerebral veins. The patient underwent digital subtraction angiography (DSA), which showed a prominent left posterior cerebral artery (PCA) with associated flow-related aneurysm in the P1 segment of left PCA. There was a prominent left posteromedial choroidal artery showing slow anterograde flow with stasis of contrast in the delayed capillary and venous phase. There was also non-opacification of the deep venous system in the venous phase [Figure 2]a-c]. The findings of DSA were suggestive of thrombosed vein of Galen malformation (VOGM). The patient was offered neither surgical nor endovascular treatment options, and was discharged and advised a repeat angiography at a follow up of 6 months to check for the regression of flow-related aneurysm in the P1 segment of left PCA.
|Figure 1: Fluid attenuated inversion recovery, axial image (a and b) showed a hyperintense oval lesion (arrow) in the quadrigeminal cistern and a curvilinear hyperintensity (arrows) in the third ventricle region. T1-weighted sagittal image (c) showed an oval hyperintensity in continuation (arrow) with the curvilinear hyperintensity, suggestive of the thrombosed vein of Galen aneurysm and internal cerebral veins|
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|Figure 2: Left vertebral artery injection. Arterial phase (a) showed a relatively prominent left PCA (red arrow) and a small flow-related aneurysm (yellow arrow) in P1 segment of left PCA. Late capillary phase (b) showed stasis of dye in the prominent left posterior medial choroidal artery (arrow). Venous phase (c) showed the stasis of dye in the left posterior medial choroidal artery (arrow) and non-opacification of the deep venous system|
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VOGM is a rare anomaly found in children.,, It is an arteriovenous communication between the primitive choroidal vessels and the persistent median prosencephalic vein of Markowski. Many classifications have been described in the literature. The most commonly used and accepted classification systems are those proposed by Yasargil  and Lasjaunias. Yasargil described lesion types 1, 2, and 3, which are direct fistulae between the malformations and the vein of Galen. Lesion type 4 is a parenchymal arteriovenous malformation, which drains directly into the vein of Galen. Lasjaunias et al., divided these malformations into the choroidal and the mural types. The choroidal type is a high-flow type having multiple fistulae at the anterior and terminal segment of the median prosencephalic vein. The mural type is the slow-flow type having a fistula at the inferior wall of the median prosencephalic vein. The occurrence of VOGM is very rarely seen in adults and has been reported by some authors in the literature., Some authors , have also reported the rare presentation of spontaneous thrombosis of VOGM in adults. In our case, there was spontaneous thrombosis of the choroidal type of VOGM, which was incidentally diagnosed on MRI and DSA. There are various risk factors described in the literature that are known to promote the thrombosis of VOGM.,,
We report a rare case of spontaneous thrombosis of VOGM in a young adult who presented with severe headache. No treatment, including microsurgery and endovascular surgery, was offered to the patient in view of the spontaneous thrombosis of the malformation. This entity should be kept in the differential diagnosis of severe headache in a young adult.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
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Conflicts of interest
There are no conflicts of interest.
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