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NEUROIMAGES
Year : 2019  |  Volume : 67  |  Issue : 5  |  Page : 1395

Temporal Variant Frontotemporal Dementia


Department of Neurology, Soonchunhyang University School of Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea

Date of Web Publication19-Nov-2019

Correspondence Address:
Dr. Kyum-Yil Kwon
Department of Neurology, Soonchunhyang University School of Medicine, 59 Daesagwan-ro, Yongsan-gu, Seoul 04401
Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.271255

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How to cite this article:
Kwon KY. Temporal Variant Frontotemporal Dementia. Neurol India 2019;67:1395

How to cite this URL:
Kwon KY. Temporal Variant Frontotemporal Dementia. Neurol India [serial online] 2019 [cited 2019 Dec 9];67:1395. Available from: http://www.neurologyindia.com/text.asp?2019/67/5/1395/271255




Frontotemporal dementia (FTD) is an uncommon neurodegenerative disorder, which is clinically and pathologically heterogeneous. A 59-year-old man was admitted to the hospital because of slow progressive behavioral changes including disinhibition and memory disturbance for a period of five years. He had no familial history of neurological disorder. A detailed neuropsychological test showed episodic memory and frontal executive dysfunctions. Magnetic resonance imaging revealed marked volume loss only in the bilateral anterior temporal lobe, and which was worse on the right side as compared to the left [Figure 1].[1] A recent study reported that temporal variant FTD is related to globular glial tauopathy, which is a rare pathology for FTD.[2]
Figure 1: Fluid-attenuated inversion recovery axial and T2-weighted coronal images show marked atrophy in bilateral anterior temporal lobe without atrophy in the frontal lobe. Anterior temporal atrophy is more severe on the right versus the left side

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Soonchunhyang University Research Fund.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Shimizu H, Hokoishi K, Fukuhara R, Komori K, Ikeda M. Two cases of frontotemporal dementia with predominant temporal lobe atrophy. Psychogeriatrics 2009;9:204-7.  Back to cited text no. 1
    
2.
Clark CN, Lashley T, Mahoney CJ, Warren JD, Revesz T, Rohrer JD. Temporal variant frontotemporal dementia is associated with globular glial tauopathy. Cogn Behav Neurol 2015;28:92-7.  Back to cited text no. 2
    


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