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Year : 2010  |  Volume : 58  |  Issue : 5  |  Page : 813--814

Large cystic target lesion: An unusual presentation of cavernoma

Chhitij Srivastava1, Sunil K Singh1, Bal Krishna Ojha1, Anil Chandra1, Swati Srivastava2,  
1 Department of Neurosurgery, CSM Medical University, Formerly King George's Medical College, Lucknow - 226 003, U.P, India
2 Department of Pathology, Vivekanand Polyclinic Institute of Medical Science, Lucknow - 226 007, U.P, India

Correspondence Address:
Chhitij Srivastava
Department of Neurosurgery, CSM Medical University, Formerly King George«SQ»s Medical College, Lucknow - 226 003, U.P

How to cite this article:
Srivastava C, Singh SK, Ojha BK, Chandra A, Srivastava S. Large cystic target lesion: An unusual presentation of cavernoma.Neurol India 2010;58:813-814

How to cite this URL:
Srivastava C, Singh SK, Ojha BK, Chandra A, Srivastava S. Large cystic target lesion: An unusual presentation of cavernoma. Neurol India [serial online] 2010 [cited 2020 Jul 3 ];58:813-814
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Full Text


Imaging characteristics of a large cavernoma are variable; they may be purely cystic or contrast-enhancing mass lesions. [1],[2],[3] This report presents a cavernoma with a large cystic target lesion with central core enhancement.

A 30-year-old lady presented with recurrent seizure, headache and left hemiparesis. Contrast computerized tomography (CCT) brain showed a well-defined lesion resembling the target of shooting rifle with central enhancing core and a well-demarcated surrounding hypodense halo along with perilesional edema [Figure 1]. On magnetic resonance imaging (MRI), the central core demonstrated mixed intensity on both T1- and T2-weighted images; the surrounding halo was isointense on T1W and hyperintense on T2W images with blooming on Gradient Echo sequences. Contrast study showed irregular enhancement of central core, while the peripheral rim of halo was perfectly spherical and brilliantly enhancing [Figure 2]. Cerebral angiogram revealed no abnormality.{Figure 1}{Figure 2}

At surgery, xanthochromic fluid was aspirated from the cystic lesion. Wall of the cyst was easily separable from the surrounding gliotic brain, and total excision of the lesion was done. Cut section of the specimen showed central area of soft, fragile reddish brown mass. Histopathology confirmed the diagnosis of cavernoma. At the 6-month postoperative follow-up, the patient is asymptomatic.

In brain lesions, central calcific nidus or central enhancement with surrounding enhancing ring has been considered as target sign. This sign was first described in intracerebral tuberculoma and was considered to be pathognomic of this lesion. [4] Target sign has also been reported in a case of metastatic adenocarcinoma. [5]


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