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Year : 2011  |  Volume : 59  |  Issue : 2  |  Page : 323-

Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias

V Wiwanitkit 
 Wiwanitkit House, Bangkhae, Bangkok - 10160, Thailand

Correspondence Address:
V Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok - 10160
Thailand




How to cite this article:
Wiwanitkit V. Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias.Neurol India 2011;59:323-323


How to cite this URL:
Wiwanitkit V. Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias. Neurol India [serial online] 2011 [cited 2020 Jul 8 ];59:323-323
Available from: http://www.neurologyindia.com/text.asp?2011/59/2/323/79164


Full Text

Sir,

I read with interest the article by Tripathi et al[1] on Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias with great interest. The authors concluded that Tc-99m ethylcysteinate dimer brain perfusion SPECT is useful in the differential diagnosis of dementia with particular reference to Alzheimer's disease (AD) as well as frontotemporal dementia (FTD). I would like to share some of my views on this topic. First, although the diagnostic criterion for various diseases is appropriate, I have an important concern for the small number of subjects in each group. Indeed, in case with enlarged ventricle, the false positive can be expected. [2] Second, the cost-effectiveness of this new approach is interesting. If possible, data on this aspect may be given.

References

1Tripathi M, Tripathi M, Vibha D, Gowda N, Bal C, Malhotra A. Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias. Neurol India 2010;58:857-62.
2Kobayashi S, Tateno M, Utsumi K, Takahashi A, Morii H, Saito T. Two-layer appearance on brain perfusion SPECT in idiopathic normal pressure hydrocephalus: A qualitative analysis by using easy Z-score imaging system, eZIS. Dement Geriatr Cogn Disord 2009;28:330-7.