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Year : 2016  |  Volume : 64  |  Issue : 6  |  Page : 1377--1378

Conventional MRI demonstration of thalamic internal medullary laminae and a few nuclei in a case of multifocal glioma

Kamble J Harsha 
 Department of Clinical Neurosciences, Indo-American Hospital, Brain and Spine Centre, Chemmanakary, Kerala, India

Correspondence Address:
Kamble J Harsha
Department of Clinical Neurosciences, Indo-American Hospital, Brain and Spine Centre, Chemmanakary- 686 143, Vaikom, Kerala
India




How to cite this article:
Harsha KJ. Conventional MRI demonstration of thalamic internal medullary laminae and a few nuclei in a case of multifocal glioma.Neurol India 2016;64:1377-1378


How to cite this URL:
Harsha KJ. Conventional MRI demonstration of thalamic internal medullary laminae and a few nuclei in a case of multifocal glioma. Neurol India [serial online] 2016 [cited 2020 Jul 10 ];64:1377-1378
Available from: http://www.neurologyindia.com/text.asp?2016/64/6/1377/193799


Full Text

A 40-year-old female patient presented with an episode of generalized tonic-clonic seizure. Her magnetic resonance imaging (MRI) revealed a multifocal low grade glioma involving the left anterior cingulate gyrus and bilateral thalami. Interestingly, T2-weighted MRI showed the prominence of bilateral internal medullary laminae (IML) of thalami (Right > Left) [Figure 1]. The right internal medullary lamina was extending anteriorly to enclose the anterior group of nuclei (A); and, also extending posteriorly, dividing the ventral posterior nucleus and the pulvinar. The right ventral posterior nucleus had a relative hypointense appearance when compared to the ventral lateral nucleus, with a sharp demarcation existing between the two groups. The imaging findings were suggestive of a “coffee bean” appearance.{Figure 1}

Thalamus is a part of the limbic system that connects the cerebral cortex with other parts of the brain. It is structurally composed of several groups of neurons (nuclei), each with its distinct connection. The differentiation between the nuclei is routinely not possible with the conventional MRI sequences. The medial nuclear involvement in isolation or along with the pulvinar is commonly identified in MRI in certain encephalitis (viral,[1] and paraneoplastic [2]) and in Creutzfeldt–Jakob disease.[3] Apart from these conditions, the differentiation between the different groups of nuclei or the demonstration of internal medullary laminae is difficult. The segmentation technique based on tensorial morphological gradient of diffusion tensor imaging is useful in demonstrating thalamic nuclei; however, this technique is mainly limited for research.[4] The prominence of internal medullary lamina in our case was possibly due to it being spared by the glioma. In addition, the differential involvement of the right ventral anterior and lateral nuclei with relative sparing of the ventral posterior nuclei gave the appearance of the presence of separate nuclei groups. Gliomas and glioblastomas have a tendency to spread along the white matter tracts; the differential spread in the current case (by sparing of bilateral internal medullary laminae and relative sparing of the right ventral posterolateral nucleus) had enhanced the gross anatomical details of the thalamic nuclei on conventional MRI. Under normal circumstances, these nuclei would be extremely difficult to identify with the conventional MRI sequences.

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Conflicts of interest

There are no conflicts of interest.

References

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