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CASE REPORT
Year : 2019  |  Volume : 67  |  Issue : 4  |  Page : 1093--1096

Drug Refractory Epilepsy – A Series of Lesions with Triple Pathology

Vivek Tandon1, Poodepedi Sarat Chandra1, Raghav Singla1, Jitin Bajaj1, Aanchal Kakkar2, Mehar Chand Sharma2, Ashok Kumar Mahapatra1, Manjari Tripathi3 
1 Department of Neurosurgery, Cardioneurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
2 Department of Neuropathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
3 Department of Neurology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India

Correspondence Address:
Dr. Poodepedi Sarat Chandra
Department of Neurosurgery, Room No. 720, Cardioneurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
India

The associations between gangliogliomas, dysembryoplastic neuroepithelial tumors (DNETs), and cortical dysplasias remain debatable. We report five cases of drug refractory epilepsy with temporal lobe lesions. On resection, histopathological examination showed distinctive areas of gangliogliomas and DNETs with cortical dysplasia. The coexistence of the above three lesions as distinct entities in a single lesion is virtually unknown. This points to the presence of a possible etiological relationship among them. Finally, we also delve into a plausible hypothesis for such a pathogenesis.


How to cite this article:
Tandon V, Chandra PS, Singla R, Bajaj J, Kakkar A, Sharma MC, Mahapatra AK, Tripathi M. Drug Refractory Epilepsy – A Series of Lesions with Triple Pathology.Neurol India 2019;67:1093-1096


How to cite this URL:
Tandon V, Chandra PS, Singla R, Bajaj J, Kakkar A, Sharma MC, Mahapatra AK, Tripathi M. Drug Refractory Epilepsy – A Series of Lesions with Triple Pathology. Neurol India [serial online] 2019 [cited 2019 Oct 15 ];67:1093-1096
Available from: http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2019;volume=67;issue=4;spage=1093;epage=1096;aulast=Tandon;type=0