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Year : 2020  |  Volume : 68  |  Issue : 1  |  Page : 238--239

Intracranial Hodgkin's Lymphoma

Eva Koubska1, Jiri Weichet2, Hana Malikova2,  
1 Radiology Department of Third Faculty of Medicine, Charles University in Prague and Faculty Hospital Kralovske Vinohrady in Prague; First Medical Faculty, Charles University in Prague, Czech Rep
2 Radiology Department of Third Faculty of Medicine, Charles University in Prague and Faculty Hospital Kralovske Vinohrady in Prague, Czech Rep

Correspondence Address:
Dr. Hana Malikova
Radiology Department of Third Faculty of Medicine, Charles University and Faculty Hospital Kralovske Vinohrady in Prague, Srobarova 50, Prague . 10034
Czech Rep




How to cite this article:
Koubska E, Weichet J, Malikova H. Intracranial Hodgkin's Lymphoma.Neurol India 2020;68:238-239


How to cite this URL:
Koubska E, Weichet J, Malikova H. Intracranial Hodgkin's Lymphoma. Neurol India [serial online] 2020 [cited 2020 Jun 2 ];68:238-239
Available from: http://www.neurologyindia.com/text.asp?2020/68/1/238/279692


Full Text



A 33-year-old woman suffered from right-side hearing loss, headache, and vertigo. On MRI, two intracranial lesions were found, both arising from dura. One lesion was situated in the right temporo-occipital area, the second on the right tentorium with supratentorial and infratentorial propagation. Both lesions showed low signal on T1WI and T2WI with significant postcontrast enhancement with no signs of diffusion restriction. Lesions were surrounded by vasogenic edema [Figure 1]A. Moreover, there was a tumorous infiltration of parotid regions on both sides, soft tissue masses in the right external meatus and the middle ear cavity and partly infiltrated left mastoid cells [Figure 1]B. The diagnosis of the lymphoma was suggested. The biopsy of the infiltrated parotid gland proved surprisingly Hodgkin's lymphoma (HL) [Figure 2]. Haemato-oncology treatment was initiated and one month later the partial regression of brain lesions was apparent [Figure 3].{Figure 1}{Figure 2}{Figure 3}

Intracranial affection by HL is very rare, estimated less than 0.5% of all HL cases, usually reported as case reports.[1],[2] Opposed to the demonstrated case, absolute majority of brain lymphomas are non-Hodgkin's lymphomas manifested as multiple parenchymal lesions with diffusion restriction and strong gadolinium contrast enhancement.[3],[4],[5] Both isolated meningeal affections and free diffusion are rare.[4],[5]

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

HM and JW are supported by Charles University research program PROGRES Q28.

Conflicts of interest

There are no conflicts of interest.

References

1Hirmiz K, Foyle A, Wilke D, Burrell S, Brownstone R, Ago C, et al. Intracranial presentation of systemic Hodgkin's disease. Leuk Lymphoma 2004;45:1667-71.
2Vera R Jr, Enriquez R, Papac R. Hodgkin's disease, intracranial involvement. Report of a case and review of the literature. Am J Clin Oncol 1985;8:73-6.
3Agarwal PA, Menon S, Smruti BK, Singhal BS. Primary central nervous system lymphoma: A profile of 26 cases from Western India. Neurol India 2009;57:756-63.
4Malikova H, Koubska E, Weichet J, Klener J, Rulseh A, Liscak R, et al. Can morphological MRI differentiate between primary central nervous system lymphoma and glioblastoma? Cancer Imaging 2016;16:40.
5Koubska E, Weichet J, Malikova H. Central nervous system lymphoma: A morphological MRI study. Neuroendocrinol Lett 2016;37:318-24.