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Figure 3: Case 3. Magnetic resonance imaging (MRI) T1 post-gadolinium coronal section showing an enhancing mass lesion with predominantly solid and a little cystic area in the pineal region (a; MRI). Histophotomicrographs (b and c: H and E, × 100; d and e: H and E, × 400) show a tumor composed of polygonal shaped tumor cells arranged predominantly in nests, sheets and papillae in a background of loose edematous non-fibrillary stroma. The tumor was immunoreactive for vimentin (f; IHC), p53 (i; IHC, moderate intensity), Bcl-2 (j; IHC), S-100 protein (k; IHC, cytoplasmic) and NSE (h; IHC), while it was negative for EMA (n; IHC), synaptophysin (m; IHC), GFAP (l; IHC) and CK (g; IHC). MIB-1 LI (o; IHC) was 1-2%

Figure 3: Case 3. Magnetic resonance imaging (MRI) T1 post-gadolinium coronal section showing an enhancing mass lesion with predominantly solid and a little cystic area in the pineal region (a; MRI). Histophotomicrographs (b and c: H and E, × 100; d and e: H and E, × 400) show a tumor composed of polygonal shaped tumor cells arranged predominantly in nests, sheets and papillae in a background of loose edematous non-fibrillary stroma. The tumor was immunoreactive for vimentin (f; IHC), p53 (i; IHC, moderate intensity), Bcl-2 (j; IHC), S-100 protein (k; IHC, cytoplasmic) and NSE (h; IHC), while it was negative for EMA (n; IHC), synaptophysin (m; IHC), GFAP (l; IHC) and CK (g; IHC). MIB-1 LI (o; IHC) was 1-2%