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Figure 1: MRI (brain) of patient 1 initially and after 3 months of stopping tinidazole revealing: T1W axial image (initial A) showing caudate hypodensity which was enhancing with gadolinium (inset Ag) and at follow-up (a) there was hyperintensity of caudate and was non-enhancing (inset ag); T2W (B, b) and FLAIR (C, c) axial sequence during the initial period showed hyperintensity of caudate, putamen and splenium which decreased during the serial scans; sagittal T2W image showing splenial signal change (D) which decreased partially at follow-up (d); axial T2W image showing dentate involvement during the initial scan (E) with complete resolution at follow-up (e); f: diffusion-weighted image and apparent diffusion coefficient showing restriction of the splenial lesion

Figure 1: MRI (brain) of patient 1 initially and after 3 months of stopping tinidazole revealing: T1W axial image (initial A) showing caudate hypodensity which was enhancing with gadolinium (inset Ag) and at follow-up (a) there was hyperintensity of caudate and was non-enhancing (inset ag); T2W (B, b) and FLAIR (C, c) axial sequence during the initial period showed hyperintensity of caudate, putamen and splenium which decreased during the serial scans; sagittal T2W image showing splenial signal change (D) which decreased partially at follow-up (d); axial T2W image showing dentate involvement during the initial scan (E) with complete resolution at follow-up (e); f: diffusion-weighted image and apparent diffusion coefficient showing restriction of the splenial lesion