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Figure 1: Basal view of the brain showing thick basal exudate filling the basal cisterns, and obscuring the basilar artery (*, a). Note the entrapped internal carotids (arrows), optic and oculomotor nerves. The exudate on histology reveals necrotizing granulomatous inflammation entrapping vessels (V) in the subarachnoid space (b). Note the extension of the granuloma into the parenchyma breaching the pia. Spectrum of vascular changes seen with granulomatous inflammation in the vessel wall (c), fibrinoid necrosis in smaller parenchymal venules (d) and concentric thickening with endarteritic changes causing luminal compromise in the chronic phase (e). Vascular smooth muscle shows prominent vacuolation (f) reflecting vasospasm

Figure 1: Basal view of the brain showing thick basal exudate filling the basal cisterns, and obscuring the basilar artery (*, a). Note the entrapped internal carotids (arrows), optic and oculomotor nerves. The exudate on histology reveals necrotizing granulomatous inflammation entrapping vessels (V) in the subarachnoid space (b). Note the extension of the granuloma into the parenchyma breaching the pia. Spectrum of vascular changes seen with granulomatous inflammation in the vessel wall (c), fibrinoid necrosis in smaller parenchymal venules (d) and concentric thickening with endarteritic changes causing luminal compromise in the chronic phase (e). Vascular smooth muscle shows prominent vacuolation (f) reflecting vasospasm