Neurol India Close
 

Figure 5: (a-h) Papillary tumor of pineal region (WHO grade III). (a-d) Tumor of papillary architecture lined by columnar and polygonal cells with cytoplasmic vacuolation and areas of necrosis [H and E: (a) ×100, (b and c) ×400, (d) ×200], (e) positivity for AE1/AE3 (IHC × 200), (f) MIB1 labeling index of 10%–12% (IHC × 100), (g and h) metastatic site displaying focal papillary architecture and areas resembling pineoblastoma with numerous mitosis (encircled) and rosettes (arrow) [H and E: (g) ×200, (h) ×400]

Figure 5: (a-h) Papillary tumor of pineal region (WHO grade III). (a-d) Tumor of papillary architecture lined by columnar and polygonal cells with cytoplasmic vacuolation and areas of necrosis [H and E: (a) ×100, (b and c) ×400, (d) ×200], (e) positivity for AE1/AE3 (IHC × 200), (f) MIB1 labeling index of 10%–12% (IHC × 100), (g and h) metastatic site displaying focal papillary architecture and areas resembling pineoblastoma with numerous mitosis (encircled) and rosettes (arrow) [H and E: (g) ×200, (h) ×400]