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Figure 11: Microphotograph showing (a-c) skin biopsy and (d-f) nerve biopsy features of systemic sclerosis. (a-c) Atrophic epidermis, dense fibrosis of dermis entrapping sweat glands (a, b arrow). The fibrosis is highlighted on Masson trichrome stain (MAT). The dermal vessels show marked medial hypertrophy with luminal occlusion (c), a feature of occlusive arteriopathy; (d-f) Epineurial vessels with occlusive arteriopathy. Myelin stain shows small diameter fibre loss

Figure 11: Microphotograph showing (a-c) skin biopsy and (d-f) nerve biopsy features of systemic sclerosis. (a-c) Atrophic epidermis, dense fibrosis of dermis entrapping sweat glands (a, b arrow). The fibrosis is highlighted on Masson trichrome stain (MAT). The dermal vessels show marked medial hypertrophy with luminal occlusion (c), a feature of occlusive arteriopathy; (d-f) Epineurial vessels with occlusive arteriopathy. Myelin stain shows small diameter fibre loss