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Figure 2: A simple illustration of the experimental flow for creation of the simulated conditions and the HU-ground animal model. (A) Employment of normal rodent used in animal studies. (B) Normal rodent kept in a cage with its hind limbs not touching the cage surface, over a time period (2 months maximum), thus creating MG conditions simulating situations where astronauts lose their ability to contact the floor surface using their lower limbs. This is called the HU ground-based animal model. Technical details of the HU ground-based animal models have been described by Morey.[28] (C) During this period, various changes occurring in the nervous system can be studied

Figure 2: A simple illustration of the experimental flow for creation of the simulated conditions and the HU-ground animal model. (A) Employment of normal rodent used in animal studies. (B) Normal rodent kept in a cage with its hind limbs not touching the cage surface, over a time period (2 months maximum), thus creating MG conditions simulating situations where astronauts lose their ability to contact the floor surface using their lower limbs. This is called the HU ground-based animal model. Technical details of the HU ground-based animal models have been described by Morey.[28] (C) During this period, various changes occurring in the nervous system can be studied