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Figure 3: Axial T2 weighted (a), gadolinium-enhanced T1 weighted (b) images demonstrating the peripherally enhancing centrally necrotic high- grade glioma with peripheral hyperperfusion on dynamic susceptibility contrast imaging (c). Note that the metabolite map showing raised choline on spectroscopy (d) indicates that the solid enhancing zones are the mitotic zones and should always be included in defining the target area for GKRS

Figure 3: Axial T2 weighted (a), gadolinium-enhanced T1 weighted (b) images demonstrating the peripherally enhancing centrally necrotic high- grade glioma with peripheral hyperperfusion on dynamic susceptibility contrast imaging (c). Note that the metabolite map showing raised choline on spectroscopy (d) indicates that the solid enhancing zones are the mitotic zones and should always be included in defining the target area for GKRS