|Year : 1998 | Volume
| Issue : 3 | Page : 204--211
POEMS syndrome : a clinico pathological study.
A Vasanth, KPS Nair, AB Taly, PN JayakuJan-Mar, SK Shankar
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560 029, India
Clinical features of five patients with POEMS syndrome and one with Castleman's disease, who presented with chronic, progressive motor sensory peripheral neuropathy are described. Papilloedema was seen in all patients with POEMS syndrome. Four of them also had bone lesions, biopsy of which established the diagnosis. Lymph node biopsy revealed angiofollicular lymphoid hyperplasia in the patient with Castleman's disease. Response to therapy was not satisfactory. The clinical features are compared with other reported series. A high index of suspicion, meticulous clinical examination and investigations are essential for establishing the diagnosis.
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560 029
Source of Support: None, Conflict of Interest: None
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