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| Year : 1999 | Volume
: 47
| Issue : 3 | Page : 206--9 |
Botulinum toxin treatment of hemifacial spasm and blepharospasm : objective response evaluation.
A Thussu, CR Barman, S Prabhakar
Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India., India
Correspondence Address:
A Thussu
Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 10514580 
Twenty seven patients with hemifacial spasm (HFS) and sixteen patients with blepharospasm (BS) having mean Jankovic disability rating scale score of 2.56+0.58 SD and 2.81+0.54 SD, respectively, were treated with botulinum toxin A (BTX-A) injections. The total number of injection sessions were ninety one with relief response in 98.91%. The mean improvement in function scale score was 3.78+0.64 SD and 3.29+1.07 SD respectively, in HFS and BS groups. The clinical benefit induced by botulinum toxin lasted for a mean of 4.46+3.11 SD (range 2 to 13) months in HFS group and 2.66+1.37 SD (range 1 to 6) months, in BS groups. Transient ptosis was seen in 4.39% of total ninety one injection sessions. These findings show that local botulinum toxin treatment provides effective, safe and long lasting relief of spasms.
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