Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 571  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 »   Next article
 »   Previous article
 »   Table of Contents

 Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 3    

Recommend this journal


Year : 1999  |  Volume : 47  |  Issue : 4  |  Page : 333--5

Alexander's disease : a case report of a biopsy proven case.

Department of Pathology, G.B. Pant Hospital, New Delhi, 110002, India., India

Correspondence Address:
M Tatke
Department of Pathology, G.B. Pant Hospital, New Delhi, 110002, India.
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 10625914

Rights and PermissionsRights and Permissions

A case of infantile onset Alexander's disease in a two and a half year old male child is presented, who had progressively increasing macrencephaly since birth. A frontal lobe biopsy revealed collections of Rosenthal fibres in the subpial and perivascular areas with diffuse dysmyelination and presence of reactive astrocytes. The Rosenthal fibres were immunoreactive for glial fibrillary acidic protein and ubiquitin. Electron microscopic examination showed the Rosenthal fibres as intra-astrocytic and extracellular granular osmiphilic collections.

[FULL TEXT] [PDF Not available]*

Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow