| REVIEW ARTICLE |
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| Year : 2003 | Volume
: 51
| Issue : 4 | Page : 461--465 |
The management of non-functioning pituitary adenomas
J A Jr. Jane, E R Jr. Laws
Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA
Correspondence Address:
E R Jr. Laws
Department of Neurosurgery, Box 800212, University of Virginia Health System, Charlottesville, Virginia
USA
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 14742922 
Non-functioning pituitary adenomas most commonly present secondary to mass effect and are classified according to their size and immunohistochemical staining. Local intrasellar mass effect may cause varying degrees of hypopituitarism. With extrasellar growth, neurological signs and symptoms develop. Appropriate therapy for these tumors requires close interaction across multiple disciplines. Trans-sphenoidal surgery offers safe and effective treatment in the overwhelming majority of patients with relatively low risk of new neurological and endocrinologic deficits. The multidisciplinary management of non-functioning adenomas, their diagnosis and therapeutic outcomes, is discussed.
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