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Year : 2003  |  Volume : 51  |  Issue : 4  |  Page : 554--556

Steroid-induced myopathy following a single oral dose of prednisolone

Neurology Unit, Department of Neurological Sciences, Christian Medical College Hospital, Vellore - 632004, Tamil Nadu, India

Correspondence Address:
S Kumar
Department of Neurological Sciences, Christian Medical College Hospital, Vellore - 632004
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Source of Support: None, Conflict of Interest: None

PMID: 14742951

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This report describes a case of acute steroid-induced myopathy following a single dose of oral prednisolone. A 55-year-old man presented with an acute exacerbation of chronic obstructive pulmonary disease (COPD), which was treated with prednisolone 40 mg daily in addition to bronchodilators. He developed features of myopathy the next day. Serum CPK was moderately elevated and electromyogram (EMG) was suggestive of primary muscle disease. He was managed conservatively and improved 10 days after stopping prednisolone. Mechanisms of steroid-induced myopathy and relevant literature have been reviewed.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow