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LETTER TO EDITOR
Year : 2005  |  Volume : 53  |  Issue : 1  |  Page : 120

Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome


Movement Disorders Program, Foothills Hospital, University of Calgary, Alberta, Canada

Date of Acceptance03-Mar-2005

Correspondence Address:
M A Joy
Movement Disorders Program, Foothills Hospital, University of Calgary, Alberta
Canada
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.15079

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How to cite this article:
Joy M A. Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurol India 2005;53:120

How to cite this URL:
Joy M A. Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurol India [serial online] 2005 [cited 2022 Aug 16];53:120. Available from: https://www.neurologyindia.com/text.asp?2005/53/1/120/15079


Sir,

I read with interest the report of acute reversible extrapyramidal syndrome presumably caused by vitamin B12 deficiency by Sudhir Kumar.[1] If this finding can be replicated, we may have another neurological manifestation caused by deficiency of vitamin B12. Probably from now on we should look for extrapyramidal manifestations in patients with deficiency of this vitamin.

Dr. Sudhir's report also tells the importance of giving credence to simple investigations like complete blood count and peripheral smear examination. This could give unexpected and remarkable results as far as treatment is concerned at least in a few number of patients. Such observations could go a long way as far as clinical medicine is concerned.

I have a slight objection to the statement made by Kumar about the diagnosis. He states in the case report section "a diagnosis of acute onset  Parkinsonism More Details with mild myeloneuropathy secondary to vitamin B12 deficiency was made" during the initial stage when the patient was seen. Because there had never been any report in the literature of such an observation in the past, it would have been difficult to attribute the patient's symptoms and signs to vitamin B12 deficiency after the initial evaluation. But once we see that the patient responds to treatment, we can presume that probably, the manifestations were due to the vitamin deficiency.

 
  References Top

1.Kumar S. Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome. Neurol India 2004;52:507-9.  Back to cited text no. 1    




 

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