| BRIEF REPORT |
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| Year : 2009 | Volume
: 57
| Issue : 3 | Page : 313--319 |
Intra-arterial thrombolysis in basilar artery occlusions combination of intra-arterial thrombolytics and Gp IIb/IIIa inhibitors in basilar artery thrombosis
SB Gaikwad1, MV Padma2, EJ Moses1, Kanika Sethi1, M Tripathi2, R Bhatia2, K Prasad2, NK Mishra1
1 Department of Neuroradiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi -110 029, India
2 Department of Neurology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi -110 029, India
Correspondence Address:
S B Gaikwad
Department of Neuroradiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi -110 029,
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.53291
Basilar artery thrombosis has high morbidity and mortality. Though intra-arterial thrombolytics have proven efficacy in the treatment of acute basilar artery occlusion, the elevation of procoagulant factors in the blood after intra-arterial thrombolysis could result in subsequent thrombus formation and clinical deterioration. Glycoprotein IIb/IIIa inhibitors have been shown to reduce this elevation in procoagulants. We present a pilot study of three cases of acute basilar artery occlusion treated with a combination of intra-arterial thrombolytics and Gp IIb/IIIa inhibitor with remarkable clinical recovery seen in all the patients.
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