| Article Access Statistics | | | Viewed | 4246 | | | Printed | 143 | | | Emailed | 3 | | | PDF Downloaded | 326 | | | Comments | [Add] | | | Cited by others | 9 | | |
|
Click on image for details.
|
|
| NEUROIMAGE |
|
|
|
| Year : 2009 | Volume
: 57
| Issue : 3 | Page : 359-360 |
Intracranial epidermoid cyst: Magnetic resonance imaging features
Rima Kumari1, Bhuvnesh Guglani2, Nitij Gupta2, Sujata Chaturvedi3
1 Department of Neuroradiology, Focus 3T MR Imaging and Research Center, Delhi - 95, India
2 Department of Neuropathology, Institute of Human Behaviour and Allied Sciences, Dilshad Garden, Delhi - 95, India
3 Institute of Human Behaviour and Allied Sciences, Dilshad Garden, Delhi - 95, India
| Date of Acceptance | 18-Mar-2009 |
| Date of Web Publication | 8-Jul-2009 |
Correspondence Address:
Bhuvnesh Guglani
91, Geeta Apartment, Geeta colony, Delhi - 110 031
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.53266
How to cite this article:
Kumari R, Guglani B, Gupta N, Chaturvedi S. Intracranial epidermoid cyst: Magnetic resonance imaging features. Neurol India 2009;57:359-60 |
A 27-year-old young male presented with a five- year history of headache and seizures with recent onset tingling and numbness in the right upper limb. Magnetic resonance imaging (MRI) revealed a large nonenhancing well-marginated extra-axial mass in the left frontotemporal region. On T1-weighted image the lesion showed mixed intensity reticulated appearance with interspersed hyperintense areas and it was hyperintense on T2-weighted (T2W) and diffusion-weighted images (DWI) [Figure 1]. At surgery, a cyst with viscous, pearly white contents was removed. Microscopic examination of the cyst revealed keratinizing squamous epithelium with keratinous debris arranged in laminated layers with many anucleate squames [Figure 2].
Epidermoids are rare benign, congenital, developmental tumors, usually located in the cerebellopontine angle and parasellar regions. The epidermoid cysts are thin walled and lined by stratified squamous epithelium. The typical MR image appearance of epidermoid tumors is hypo- to slight hyperintense on T1W images, iso- to hyperintense on T2W images, and hyperintense on DWI. [1],[2] Uncommonly on T1W images the epidermoids are hyperintense and on T2W images are of low signal intensity. Rarely on computed tomography (CT) epidermoids are hyperdense or calcified. [1],[2],[3]
No definite relation between signal intensity on T1W images and the concentration of cholesterol and triglycerides within epidermoids has been found. However, high concentration of protein is thought to be responsible for an increase in signal intensity on T1W images. [2],[3]
In this patient, the unusual MR imaging characteristics on T1W images may be explained by the high protein concentration with lamellar keratin flakes causing the honeycomb-like reticulated appearance. MRI with DW imaging is helpful to distinguish epidermoids from other cystic tumors, improving the specificity of diagnosis. [4]
| » References | |  |
| 1. | Gualdi GF, Di Biasi C, Trasimeni G, Pingi A, Vignati A, Maira G. Unusual MR and CT appearance of an epidermoid tumor. AJNR Am J Neuroradiol 1991;12:771-2.  [PUBMED] |
| 2. | Kallmes DF, Provenzale JM, Cloft HJ, McClendon RE. Typical and atypical MR imaging features of intracranial epidermoid tumours. AJR Am J Roentgenol 1997;169:883-7. [PUBMED] [FULLTEXT] |
| 3. | Ochi M, Hayashi K, Hayashi T, Morikawa M, Ogino A, Hashmi R, et al. Unusual CT and MR appearance of an epidermoid tumour of the cerebellopontine angle. AJNR Am J Neuroradiol 1998;19:1113-5. [PUBMED] [FULLTEXT] |
| 4. | Aribandi M, Wilson NJ. CT and MR imaging features of intracerebral epidermoid- a rare lesion. Br J Radiol 2008;81:e97-9. [PUBMED] [FULLTEXT] |
[Figure 1], [Figure 2]
| This article has been cited by | | 1 |
Pituitary infundibular epidermoid cyst: a rare cause of hypopituitarism |
|
| Sajjad Ahmad, Ashutosh Surya, Caroline Hayhurst, Stephen Davies | | BMJ Case Reports. 2021; 14(3): e241065 | | [Pubmed] | [DOI] | | | 2 |
Intrakraniyal Epidermoid Tümörlerin Cerrahi Tedavisi: Cerrahi Olarak Tedavi Edilen 29 Hastanin Retrospektif Analizi |
|
| Kadir OKTAY, Ebru GUZEL, Adnan DEMIRCI, Özlem Nuray SEVER, Vildan KAYA, Elif AKPINAR, Mustafa YILDIRIM, Aslan GÜZEL, Hakan SEÇKIN | | Pamukkale Medical Journal. 2020; | | [Pubmed] | [DOI] | | | 3 |
Mixed Signal Intensity on Preoperative T1 MRI Might be Associated with Delayed Postoperative Hemorrhage in Patients with Intracranial Epidermoid Cyst |
|
| Xueyun Deng, Jiuhong Li, Daibo Ke, Lihua Liu, Junpeng Ma, Jian Cheng, Xuhui Hui | | World Neurosurgery. 2020; 133: e218 | | [Pubmed] | [DOI] | | | 4 |
Cholesteatoma in the Sellar Region Presenting as Hypopituitarism and Diabetes Insipidus |
|
| Xiangyi Kong,Huanwen Wu,Wenbin Ma,Yongning Li,Bing Xing,Yanguo Kong,Renzhi Wang | | Medicine. 2016; 95(10): e2938 | | [Pubmed] | [DOI] | | | 5 |
A fully thrombosed giant posterior inferior cerebellar aneurysm mimicking an intracranial tumour in a child |
|
| Lan, Z.G. and Ma, L. and Duan, J. and You, C. | | British Journal of Neurosurgery. 2012; 26(6): 888-890 | | [Pubmed] | | | 6 |
A fully thrombosed giant posterior inferior cerebellar aneurysm mimicking an intracranial tumour in a child |
|
| Zhi Gang Lan,Lu Ma,Jie Duan,Chao You | | British Journal of Neurosurgery. 2012; 26(6): 888 | | [Pubmed] | [DOI] | | | 7 |
Clinical characteristics and diagnostic imaging of epidermoid tumors |
|
| Daniel Nagasawa, Andrew Yew, Michael Safaee, Brendan Fong, Quinton Gopen, Andrew T. Parsa, Isaac Yang | | Journal of Clinical Neuroscience. 2011; | | [VIEW] | [DOI] | | | 8 |
Extradural epidermoid cyst: Case reports and review of the literature |
|
| Chen, L.-Z., Ren, B. | | Journal of Chinese Clinical Medicine. 2010; 5(2): 111-115 | | [Pubmed] | | | 9 |
Frontal intraparenchymal "white epidermoid cyst": A rare occurrence |
|
| Diyora, B., Nayak, N., Kale, D., Kamble, H., Sharma, A. | | Journal of Neurosciences in Rural Practice. 2010; 1(2): 125-127 | | [Pubmed] | |
|
|
|
|
|
|
|
|
