Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 9555  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
  » Next article
  » Previous article 
  » Table of Contents
 Resource Links
  »  Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
  »  Article in PDF (480 KB)
  »  Citation Manager
  »  Access Statistics
  »  Reader Comments
  »  Email Alert *
  »  Add to My List *
* Registration required (free)  

  In this Article
 »  Abstract
 »  Introduction
 »  References
 »  Article Figures
 »  Article Tables

 Article Access Statistics
    PDF Downloaded1995    
    Comments [Add]    
    Cited by others 95    

Recommend this journal


Year : 2009  |  Volume : 57  |  Issue : 4  |  Page : 368-374

Management of hydrocephalus in patients with tuberculous meningitis

Department of Neurological Sciences, Christian Medical College, Vellore, India

Date of Acceptance02-Jul-2009
Date of Web Publication10-Sep-2009

Correspondence Address:
Vedantam Rajshekhar
Department of Neurological Sciences, Christian Medical College, Vellore - 632 004
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.55572

Rights and Permissions

 » Abstract 

Hydrocephalus is one of the commonest complications of tuberculous meningitis (TBM) occurring in up to 85% of children with the disease. It is more severe in children than in adults. It could be either of the communicating type or the obstructive type with the former being more frequently seen. The Vellore grading system for clinical grading of patients with TBM and hydrocephalus with grade I being the best grade and grade IV being the worst grade has been validated by several authors. The management of hydrocephalus can include medical therapy with dehydrating agents and steroids for patients in good grades and those with communicating hydrocephalus. However, surgery is required for patients with obstructive hydrocephalus and those in poor grades. Surgery can involve either a ventriculo-peritoneal shunt or endoscopic third ventriculostomy (ETV). Complications of shunt surgery in patients with TBM and hydrocephalus are high with frequent shunt obstructions and shunt infections requiring repeated revisions. ETV has variable success in these patients and is generally not advisable in patients in the acute stages of the disease. Mortality on long-term follow up has been reported to vary from 10.5% to 57.1% in those with altered sensorium prior to surgery and 0 to 12.5% in patients with normal sensorium. Surgery for patients in Vellore grade IV is usually associated with a poor outcome and high mortality and therefore, its utility in these patients is debatable

Keywords: Brain, tuberculosis, hydrocephalus, grading, management, outcome

How to cite this article:
Rajshekhar V. Management of hydrocephalus in patients with tuberculous meningitis. Neurol India 2009;57:368-74

How to cite this URL:
Rajshekhar V. Management of hydrocephalus in patients with tuberculous meningitis. Neurol India [serial online] 2009 [cited 2023 Oct 4];57:368-74. Available from:

 » Introduction Top

Tuberculous meningitis (TBM) is still a very common problem in children and adults in India. Although there has been a reduction in the number of patients with TBM, it is estimated that in India the mortality due to TBM is approximately 1.5/100,000 population. [1] Hydrocephalus is one of the most common complications of TBM. It is almost always present in patients who have had the disease for four to six weeks. [2] It is more frequent and severe in children than in adults and also occurs at an earlier stage in the disease process. [2] The management of hydrocephalus in patients with TBM is discussed based on the available literature and an algorithm is suggested at the end of this review.

Pathophysiology of hydrocephalus

Hydrocephalus in patients with TBM could be either of the communicating or the obstructive type, the former being more common. [3] In both instances, the main cause is the inflammatory exudate occupying the subarachnoid spaces or the ventricular pathways. In the earlier stages of the disease, the thick gelatinous exudates block the subarachnoid spaces in the base of the brain (notably the interpeduncular and ambient cisterns) leading to communicating hydrocephalus.[4] The exudates lead to a dense scarring of the subarachnoid spaces in the later stages of the disease again leading to communicating type of hydrocephalus. A communicating hydrocephalus can also result from the exudates blocking the arachnoid granulations which prevent the absorption of cerebrospinal fluid (CSF). The inflammation of the choroid plexus and ependyma also leads to an overproduction of CSF in the acute phase of the illness. This also contributes to the hydrocephalus and raised intracranial pressure. The obstructive type of hydrocephalus develops when the fourth ventricular outlets are blocked by the exudates or leptomeningeal scar tissue or when there is obstruction of the aqueduct either due to a strangulation of the brain stem by exudates or by a subependymal tuberculoma. Communicating type of hydrocephalus is more common in TBM than the obstructive type. Schoeman et al. [3] found that the hydrocephalus was of the communicating type in 82% of their patients with TBM.

Incidence of hydrocephalus

Initial studies using air encephalography in patients with TBM found hydrocephalus in 62% of the patients. [5] Schoeman et al. [3] found computer tomography (CT) evidence of hydrocephalus in 83% of 193 children with TBM. In a CT study, only three of 60 children and adults with TBM were found to have normal ventricles, giving an incidence of 95%. [6] Significantly, 87% of children in this study had severe hydrocephalus. Compared to an incidence of 71% in children, only 12% of adults with TBM had hydrocephalus. Thus, it is evident that hydrocephalus is more common in children with TBM compared to adults. Hydrocephalus is also more common in the later stages of the disease.

Clinical presentation

The clinical features that suggest the presence of hydrocephalus are nonspecific. In any patient with TBM with altered sensorium, hydrocephalus should be suspected irrespective of the presence or absence of papilledema. Hydrocephalus is also likely to be present in patients who are alert and who complain of increasing headache with or without vomiting and blurring of vision.

Grading of patients

Grading of patients with any disease is useful to prognosticate outcome. Although a widely used grading system exists for TBM, namely the MRC grading system [Table 1], a specific grading system did not exist for patients with TBM and hydrocephalus. We proposed a grading system (Vellore grading system) based on the presence or absence of neurological deficits and level of sensorium [Table 2]. [7] This grading system is useful to grade the patients in retrospective studies but it has some degree of subjectivity in assessing sensorium. Therefore, the grading system was modified to include the Glasgow Coma Scale.[8] The latter grading system is reproducible across different levels of clinical expertise and across different disciplines of healthcare workers and is, therefore, a more reliable system. Most importantly, both the grading systems have been shown to correlate with outcome and are hence valuable in prognosticating in the individual patients.


A contrast CT scan is the imaging of choice in sick patients, especially children, as it can be performed without anesthesia or sedation and can be done in a short time compared to a magnetic resonance imaging (MRI) scan which might require a patient to still lie for longer periods. Adequate information regarding ventricular size, subependymal seepage, presence of infarcts and tuberculomas, and presence of basal exudates can be obtained from a contrast-enhanced CT scan. Although a CT scan might indicate whether the hydrocephalus is obstructive or communicating in nature, this differentiation is not always possible. CT is therefore not useful in determining the level of CSF block in TBM. Air-encephalography remains the most reliable way of determining the level of CSF obstruction.[9] For example, in the cases where the CT scan shows dilatation of the lateral and third ventricles without a dilated fourth ventricle, it can safely be presumed that the hydrocephalus is due to obstruction to the CSF pathways in the region of the aqueduct. But if all the ventricles are dilated, then it is difficult to determine whether the hydrocephalus is due to obstruction of the fourth ventricular outlets or due to an obstruction to the CSF pathways in the basal subarachnoid spaces, unless the fourth ventricle is seen to be in communication with the cisterna magna. To make the differentiation between the two types of hydrocephalus, a dynamic study such as pneumoencephalogram or CT ventriculogram is needed. However, performing either of these investigations exposes the patient to an invasive procedure with attendant risks.

Medical management

Medical management might be offered as the first line of therapy to patients with communicating hydrocephalus. [10] This comprises steroids, dehydrating agents such as mannitol, diuretics such as frusemide, and acetazolamide to reduce CSF production. Tapering doses of dexamethasone (12 to 16mg/day) can be given for four to six weeks. Mannitol can only be used for acute decompensation and is not recommended for more than 72 hours due to the occurrence of rebound intracranial hypertension. Acetazolamide (100mg/kg) and frusemide (1mg/kg) can be given for longer periods of up to a month. Medical management is generally successful in several patients with TBM who exhibit features of raised intracranial pressure. Along with the agents mentioned above, the antituberculous therapy (ATT) also probably helps in reducing the inflammatory response leading to opening of the CSF pathways. The addition of acetazolamide and furosemide was significantly more effective in achieving normal intracranial pressure (ICP) than antituberculous drugs alone. [3] In a study from South Africa by Lamprect et al. , [10] 217 children with MRC stage II and III TBM and hydrocephalus were initially managed medically if they had communicating hydrocephalus (as determined by pneumoencephalography or air encephalograms). This strategy allowed the authors to avoid shunt surgery in over 70% of the patients. Even in the other 30% who underwent shunt surgery, 41.5% (27 patients) had obstructive hydrocephalus. So it appears prudent to suggest medical management especially in patients with better sensorium (Vellore grade II) or if they definitely have communicating hydrocephalus. However, the patients should be monitored carefully for any worsening of sensorium or lack of improvement with medical management. In this situation a shunt might have to be done promptly.

Intrathecal hyaluronidase has been tried instead of shunt surgery in some patients with TBM and hydrocephalus and shown to have some benefit in the form of improvement in sensorium. But it did not offer any advantage over shunt insertion and this therapy is presently not commonly practised. [3],[11]

Surgical management

Early attempts at surgical management of hydrocephalus in patients with TBM included repeated tapping of the ventricles through burr holes, suboccipital decompression, lateral and third ventriculostomy (open) and ventriculo-subarachnoid shunts. [12] The availability of reliable shunt systems in the early 1960s dramatically changed the management of hydrocephalus.

Indications for surgery

Patients in grades I and II should undergo surgery at the earliest. It has been shown that outcomes are better with early surgery especially in patients in the better grades. The South African group has suggested that early surgery be reserved for those with obstructive hydrocephalus and medical therapy be tried for those with communicating hydrocephalus. [10] However, one of the risks of such a strategy is that some patients undergoing medical therapy might deteriorate rapidly and have a poor outcome if shunt surgery is delayed. Medical therapy also implies continuous monitoring of the patient in the hospital for prolonged periods which might not be cost-effective.

Not all patients who undergo shunt surgery for TBM with hydrocephalus show a significant improvement in their sensorium or symptoms. It is, therefore, evident that the cause of the altered sensorium and other symptoms in these patients are not always or completely attributable to the hydrocephalus. The encephalitis that is caused by the inflammatory processes enveloping the cerebral hemispheres, the ischemia caused by the arteritis especially of the small perforators at the base of the brain probably contribute in equal if not more than equal measure to the altered sensorium. A considerable proportion of patients with TBM especially those in the poorer grades have been shown to have infarcts of the basal ganglia, thalamus and brain stem. It is the same group of patients who will also exhibit hydrocephalus on the CT scans. Thus, in grade III and IV patients, it becomes difficult to determine the cause of the alteration of sensorium.

Shunt surgery

Ventriculo-atrial (VA) shunts were the initial choice for shunt procedures. The fear of disseminating the tuberculous disease through such shunt system was dispelled by reports by Bhagwati and others, [13],[14],[15],[16] who described the successful use of VA shunts in patients with TBM. However, others have reported occasional cases of dissemination of the disease following a VA shunt. [17] There was a shift to ventriculo-peritoneal (VP) shunt in the early 1980s and since then VP shunt has remained the shunt procedure of choice for patients with TBM and hydrocephalus. Although, there is a theoretical risk of developing tuberculous peritonitis following a VP shunt, to the best of our knowledge such an occurrence has not been reported. The technique for shunt surgery does not differ from that used for hydrocephalus from any other cause.

Endoscopic third ventriculostomy

Since the popularization of endoscopic third ventriculostomy (ETV) in the mid 1990s, there has been an interest in avoiding shunts in patients with hydrocephalus with the hope that if a foreign body insertion could be avoided, the accompanying complications of a shunt (infection, blockage, extrusion, abdominal pseudocysts, skin erosion over shunt components) could also be avoided. Initially, Figaji et al. [18] and we described the use of ETV in TBM related hydrocephalus in two patients each. [19] Since then, there have been several reports on the use of ETV in these patients with varying degrees of success.

Singh et al. [20] reported a success rate of ETV in 77% of 35 patients with TBM and hydrocephalus. Also, 60% had early and 17% had delayed recovery. The success rates were not related to the type of hydrocephalus (obstructive or communicating). However, the presence of a thin and transparent floor of the third ventricle seemed to be associated with a higher success rate of 87%. Hussain et al. [21] determined that 68% of the patients with TBM and hydrocephalus benefited from various endoscopic procedures including ETV. In a more recent study by the same group they found that 19 of 26 (73%) patients with TBM and hydrocephalus responded to ETV. [22] They found that patients with longer duration of symptoms and ATT were more likely to benefit from the ETV. In contrast, Figaji et al. [23] reported a successful outcome following attempted ETV in only seven of 17 (41%) patients with TBM and hydrocephalus. In five patients, the ETV was performed but failed, whereas in another five the procedure had to be abandoned due to abnormal anatomy. They concluded that although ETV was technically possible in patients with TBM, only a surgeon experienced in endoscopic procedures should perform the surgery as the procedure is more demanding than in other situations.

In patients with TBM, the floor of the third ventricle is frequently thick and the subarachnoid space is also likely to be obliterated by exudates making it difficult to recognise anatomical landmarks. In this situation it might be prudent to abandon the procedure than risk injury to the basilar artery and its branches. We have attempted ETV in patients with TBM early in the course of disease and found that the floor of the third ventricle besides being thick is coated with small tubercles and granulation tissue that bleed when touched with even a blunt probe. As bleeding of even minor intensity can obscure the field during endoscopic procedures, we believe that ETV might be better avoided for acute hydrocephalus in patients with TBM and be reserved for either in those who have been treated with ATT for at least four weeks or in whom the disease is burnt out and the hydrocephalus has developed late. Chugh et al. [22] found that the outcome was better in those who received ATT for four weeks prior to ETV than in those operated earlier. It could also be considered in patients who have shunt failure, as it might be a better option than shunt revision in these patients.

Complications of surgery

Shunt surgery

It has been reported that complications of shunt surgery are higher in patients with TBM than in patients with other conditions. The reasons for this are the poor general condition of these patients and also the presence of higher protein and cellular content in the CSF leading to more frequent shunt obstruction. Agarwal et al. [24] reported shunt related complications in 11 (30%) children and three of 37 children had to undergo multiple shunt revisions. Palur et al. [7] reported that 26 of 114 (22.8%) patients had to undergo one or more shunt revisions, one patient requiring more than three revisions. Sil and Chatterjee [25] reported a shunt infection rate of 15.6% and revision rate of 43.8 % in their series of 37 children who underwent shunt surgery for TBM with hydrocephalus. Multiple revisions were done in 18.7% of patients.

Shunt infection and erosion of skin over the shunt components are the other major complications of shunt surgery in poor grade patients with TBM and hydrocephalus.

Endoscopic third ventriculostomy

Failure of the ETV with CSF leak and bleeding during the surgery are the most commonly reported complications of ETV. Husain et al. [21] had complications in three of 28 patients undergoing ETV for TBM related hydrocephalus. In a more recent series, the same authors have reported ETV failures in seven of 26 patients. [22] They did not report any other complications in this series of patients. Risk of injury to the basilar artery and its branches is theoretically higher in patients with TBM due to the thickened and opaque third ventricular floor.


All the early reports of shunt surgery for hydrocephalus associated with TBM report poor outcome in a proportion of patients. Bhagwati [13] reported mortality in 3 of 7 patients undergoing shunt surgery. Only 4 of 9 patients treated with the Updhyaya VA shunt improved following surgery. [15] The other 5 patients died at varying periods of time after the surgery. Palur et al. [9] reported that of the 114 patients followed up for an average of 45.6 months following shunt surgery for TBM and hydrocephalus, 48 (42.1%) died. 63 (55%) had a good outcome or moderate disability. Agarwal et al. [21] reported that 29 of 37 children (78%) had a good outcome or moderate disability at 3 months follow-up following shunt surgery for TBM and hydrocephalus. In various series of shunt surgery for TBM with hydrocephalus reported up to 1991, the mortality rate for those with altered sensorium has ranged from 10.5% to 57.1% and for those with normal sensorium has ranged from 0 to 12.5%. [7],[14],[26],[27] The mortality rates might be higher if the follow-up duration is longer as those with severe disability might go on to die. This is borne out by the fact that in our initial retrospective study, 14 of the 48 (29.1%) patients who died, did so more than one year after the surgery. [7] Therefore, while considering outcome patients discharged with severe disability should be categorized with those who have died.

Prognostic factors

In our series of patients, 114 patients who were followed up for 6 months to 13 years (mean 45.6 months) following shunt surgery for TBM with hydrocephalus, we studied various prognostic factors to predict outcome following shunt surgery. [7] Age (0-9, 10 + years), duration of altered sensorium (<15 days, >15 days), CSF cell count (<50, >50/ml), CSF protein level (<50, >50mg%), shunt revisions (0, 1 +) and bilateral shunts (0, 1), did not have any signficant effect on the long term outcome. Only the admission grade [Table 2] was highly significant ( P = 0.0001) in predicting the outcome. The presence of infarcts in the basal ganglia and internal capsule are also likely to indicate a poor outcome following shunting.

It is clear from several subsequent studies that the grade at presentation is the best and most consistent predictor of outcome following shunt surgery in patients with TBM. Agarwal et al. [24] studied 37 children with TBM and hydrocephalus who had undergone shunt surgery. They used the Vellore grading system proposed by us [Table 2] and found that all patients in grade IV were left with severe disability or died. They recommended shunt placement in all children of grade II and III as this policy has yielded the best results. For grade IV children external ventricular drainage, followed by shunting if improvement occurs remains the most cost-effective procedure.

Singh and Kumar [28] reported the outcome of VP shunt in 140 children who underwent shunt surgery for TBM and hydrocephalus. They found a good correlation between the Vellore grade at shunt surgery with the outcome. All the mortalities occurred in patients in grade IV (43/87).

In a follow-up prospective study, [8] we validated the utility of our grading system. We used an algorithm proposed in our initial article in 1991 and evaluated 32 consecutive patients with TBM and hydrocephalus in grades III or IV. We used external ventricular drainage (EVD) to select patients for VP shunt. All but one of the patients in grade IV did not improve with EVD and succumbed to the disease.

The grading system proposed by us and modified to include the GCS [Table 3] is a valid system to predict outcome following shunt surgery in patients with TBM and hydrocephalus as has been verified by several studies. [Table 4] shows the outcome in patients who underwent shunt surgery categorized using our grading system.

Sil and Chatterjee [25] noted that all patients who fared poorly following shunt surgery, in their series of 37 children with TBM and hydrocephalus, had evidence of infarcts in their CT scans. It is also likely that these patients were in the poorer Vellore grades before shunting. Stated otherwise, those in poorer grades are likely to have infarcts and therefore, infarcts on CT scan might not be an independent predictor of outcome.

Kemaloglu et al. [29] noted that patients with TBM with mild and moderate hydrocephalus who underwent early shunt surgery (two days after diagnosis) had better outcomes compared to those who had delayed surgery (three weeks after diagnosis). This effect was not seen in patients with severe hydrocephalus. While this suggests that early surgery should be offered to patients with mild and moderate hydrocephalus without delaying it while waiting to determine the effect of medical therapy, it is unclear whether shunt surgery could have been avoided in some of these patients.

TBM in HIV-positive patients and drug resistant tuberculous

In a comparative study of 30 patients with TBM and hydrocephalus, 15 being HIV-positive, it was found that mortality rate and poor outcomes at one month following shunt surgery and ATT, were considerably higher in HIV-positive patients compared to those who were HIV-negative. [30] The HIV-positive group had a mortality rate of 66.7% and poor outcome in 64.7% compared with mortality rate of 26.7% and poor outcome in 30.8% in the HIV-negative group. No patient in the HIV-positive group experienced a good recovery. No patient (either HIV-positive or HIV-negative) who presented in TBM Grade 4 survived, whereas no HIV-positive patient who presented in TBM Grade 3 survived. A significant relationship was noted between CD4 counts and patient outcomes ( P,0.031). It was suggested that HIV-positive patients with TBM should undergo a trial of ventricular or lumbar CSF drainage, and only those who show an improvement following EVD should undergo shunt surgery.

The outcome of TBM with hydrocephalus is finally dependent on the response of the disease to ATT. It is understandable that in patients with drug resistant TB either multi-drug resistant TB (MDR-TB) or extensively drug resistant TB (XDR-TB), the outcome is likely to be poor. There are however, no studies which have reported on the outcome following surgery for drug resistant TBM.

Suggested management algorithm

The main aim of the suggested algorithm is to improve the outcome of patients with TBM and hydrocephalus and also to avoid shunt surgery in those who are unlikely to benefit from the surgery [Figure 1]. The grading of the patient is important in deciding on further course of action. Although medical management could be tried for a few days or a week in patients in grades I and II, the patient should be monitored closely during this period to detect any worsening or lack of improvement and a shunt should be promptly offered in case of failure of medical management. Prolonging medical therapy in patients in good grades could be harmful and may lead to irreversible brain damage.

 » References Top

1.Chakraborty AK. Estimating mortality from tuberculous meningitis in a community: Use of available epidemiological parameters in the Indian context. Indian J Tub 2000;47:9-12.  Back to cited text no. 1    
2.Tandon PN. Tuberculous meningitis (cranial and spinal). In: Vinken PJ, Bruyn GW, editors. Handbook of Clinical Neurology. Infections of the Nervous System. vol. 33. Amsterdam: North-Holland; 1978. p. 195-262.  Back to cited text no. 2    
3.Schoeman J, Donald P, van Zyl L, Keet M, Wait J. Tuberculous hydrocephalus: Comparison of different treatments with regard to ICP, ventricular size and clinical outcome. Dev Med Child Neurol 1991;33:396-405.  Back to cited text no. 3    
4.Dastur DK, Manghani DK, Udani PM. Pathology and pathogenetic mechanisms in neurotuberculosis. Radiol Clin North Am 1995;33:733-52.  Back to cited text no. 4    
5.Lorber J. Studies of CSF circulation in tuberculous meningitis. II. A review of 100 pneumoencephalograms. Arch Dis Child 1951;26:28-48.  Back to cited text no. 5    
6.Bhargava S, Gupta AK, Tandon PN. Tuberculous meningitis-A CT scan study. Br J Radiol 1982;55:189-96.  Back to cited text no. 6    
7.Palur R, Rajshekhar V, Chandy MJ, Joseph T, Abraham J. Shunt surgery for hydrocephalous in tubercular meningitis: A long-term follow-up study. J Neurosurg 1991;74:64-9.  Back to cited text no. 7    
8.Mathew JM, Rajshekhar V, Chandy MJ. Shunt surgery for poor grade patients with tuberculous meningitis and hydrocephalus: Effect of response to external ventricular drainage and other factors on long-term outcome. J Neurol Neurosurg Psychiatry 1998;65:115-8.  Back to cited text no. 8    
9.Bruwer GE, Van der Westhuizen S, Lombard CJ, Schoeman JF. Can CT predict the level of CSF block in tuberculous hydrocephalus? Childs Nerv Syst 2004;20:183-7.  Back to cited text no. 9    
10.Lamprecht D, Schoeman J, Donald P, Hartzenberg H. Ventriculoperitoneal shunting in childhood tuberculous meningitis. Br J Neurosurg 2001;15:119-25.  Back to cited text no. 10    
11.Bhagwati SN, George K. Use of intrathecal hyaluronidase in the management of tuberculous meningitis with hydrocephalus. Childs Nerv Syst 1986;2:20-5.  Back to cited text no. 11    
12.Cairns H. Neurosurgical methods in the treatment of tuberculous meningitis. Arch Dis Child 1951;26:376-83.  Back to cited text no. 12    
13.Bhagwati SN. Ventriculoatrial shunt in tubercular meningitis with hydrocephalus. J Neurosurg 1971;35:309-13.  Back to cited text no. 13    
14.Roy TK, Sircar PK, Chandar V. Ventriculoatrial shunt in the management of tuberculous meningitis. Indian Pediatr 1979;16:1023-7.  Back to cited text no. 14    
15.Chitale VR, Kasaliwal GT. Our experience of ventriculoatrial shunt using Upadhyaya valve in cases of hydrocephalus associated with tuberculous meningitis. Prog Pediatr Surg 1982;15:223-36.  Back to cited text no. 15    
16.Upadhyaya P, Bhargava S, Sundaram KR, Mitra DK, George J, Singh DC. Hydrocephalus caused by tuberculous meningitis: Clinical picture, CT findings and results of shunt surgery. Z Kinderchir 1983;38:76-9.  Back to cited text no. 16    
17.Murray HW, Bandstetter RD, Levyne MH. Ventriculoatrial shunt for hydrocephalus complicating tuberculous meningitis. Am J Med 1981;70:895-8.  Back to cited text no. 17    
18.Figaji AA, Fieggen AG, Peter JC. Endoscopic third ventriculostomy in tuberculous meningitis. Childs Nerv Syst 2003;19:217-25.  Back to cited text no. 18    
19.Jonathan A, Rajshekhar V. Endoscopic third ventriculostomy for chronic hydrocephalus following tuberculous meningitis. Surgical Neurology 2005;63:32-4.  Back to cited text no. 19    
20.Singh D, Sachdev V, Singh AK, Sinha S. Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus: A preliminary report. Minim Invasive Neurosurg 2005;48:47-52.  Back to cited text no. 20    
21.Husain M, Jha DK, Rastogi M, Husain N, Gupta RK. Role of neuroendoscopy in the management of patients with tuberculous meningitis hydrocephalus. Neurosurg Rev 2005;28:278-83.  Back to cited text no. 21    
22.Chugh A, Husain M, Gupta RK, Ojha BK, Chandra A, Rastogi M. Surgical outcome of tuberculous meningitis hydrocephalus treated by endoscopic third ventriculostomy: Prognostic factors and postoperative neuroimaging for functional assessment of ventriculostomy. J Neurosurg Pediatr 2009;3:371-7.  Back to cited text no. 22    
23.Figaji AA, Fieggen AG, Peter JC. Endoscopy for tuberculous hydrocephalus. Childs Nerv Syst 2007;23:79-84.  Back to cited text no. 23    
24.Agrawal D, Gupta A, Mehta VS. Role of shunt surgery in pediatric tubercular meningitis with hydrocephalus. Indian Pediatr 2005;42:245-50.  Back to cited text no. 24    
25.Sil K, Chatterjee S. Shunting in tuberculous meningitis: A neurosurgeon's nightmare. Childs Nerv Syst 2008;24:1029-32.  Back to cited text no. 25    
26.Bullock MR, Van Dellen JR. The role of cerebrospinal fluid shunting in tuberculous meningitis. Surg Neurol 1982;18:274-7.  Back to cited text no. 26    
27.Gelabert M, Castro-Gago M. Hydrocephalus and tubercular meningitis in children. Child's Nerv Syst 1988;4:268-70.  Back to cited text no. 27    
28.Singh D, Kumar S. Ventriculoperitoneal shunt in post tubercular hydrocephalus. Ind Pediatr 1996;33:854-5.  Back to cited text no. 28    
29.Kemaloglu S, Ozkan U, Bukte Y, Ceviz A, Ozates M. Timing of shunt surgery in childhood tuberculous meningitis with hydrocephalus. Pediatr Neurosurg 2002;37:194-8.  Back to cited text no. 29    
30.Nadvi SS, Nathoo N, Annamalai K, van Dellen JR, Bhigjee AI. Role of cerebrospinal fluid shunting for human immunodeficiency virus-positive patients with tuberculous meningitis and hydrocephalus. Neurosurgery 2000;47:644-9.  Back to cited text no. 30    


  [Figure 1]

  [Table 1], [Table 2], [Table 3], [Table 4]

This article has been cited by
1 Lumbosacral tuberculosis, a rare manifestation of Pott's disease – How identified human skeletons from the pre-antibiotic era can be used as reference cases to establish a palaeopathological diagnosis of tuberculosis
Olga Spekker, David R. Hunt, Kitty Király, Luca Kis, Ágota Madai, Csaba Szalontai, Erika Molnár, György Pálfi
Tuberculosis. 2023; 138: 102287
[Pubmed] | [DOI]
2 Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study
Sarah U Morton, Christine Hehnly, Kathy Burgoine, Paddy Ssentongo, Jessica E Ericson, M Senthil Kumar, Cornelia Hagmann, Claudio Fronterre, Jasmine Smith, Mercedeh Movassagh, Nicholas Streck, Lisa M Bebell, Joel Bazira, Elias Kumbakumba, Francis Bajunirwe, Ronald Mulondo, Edith Mbabazi-Kabachelor, Brian K Nsubuga, Davis Natukwatsa, Esther Nalule, Joshua Magombe, Tim Erickson, Joseph Ngonzi, Moses Ochora, Peter Olupot-Olupot, Justin Onen, Peter Ssenyonga, John Mugamba, Benjamin C Warf, Abhaya V Kulkarni, Jessica Lane, Andrew J Whalen, Lijun Zhang, Kathryn Sheldon, Frederick A Meier, Julius Kiwanuka, James R Broach, Joseph N Paulson, Steven J Schiff
The Lancet Microbe. 2023;
[Pubmed] | [DOI]
3 Transcranial Doppler ultrasonography in tuberculous meningitis: A systematic review
Stephanie Patricia J. Badillo, Jose C. Navarro, Adnan I. Qureshi, Vijay K. Sharma
Journal of Neuroimaging. 2023;
[Pubmed] | [DOI]
4 Incidence and Risk Factors of Cranial Nerve Palsy in Patients with Tuberculous Meningitis: A Retrospective Evaluation
An Wen, Wen-Feng Cao, Shi-Min Liu, Yong-Liang Zhou, Zheng-Bing Xiang, Fan Hu, Ling-Feng Wu, Wen Cai, Er-Ling Leng
Infection and Drug Resistance. 2023; Volume 16: 829
[Pubmed] | [DOI]
Army Pambudi Suryo, Muhammad Arifin Parenrengi
Polski Merkuriusz Lekarski. 2023; 51(1): 95
[Pubmed] | [DOI]
6 Management of ventriculoperitoneal shunt complications in children: A review of 34 cases
RajendraKumar Ghritlaharey
African Journal of Paediatric Surgery. 2023; 20(2): 109
[Pubmed] | [DOI]
7 Development and Validation of a Prognostic Model and Bedside Score for the Neurological Outcome in Children with Tuberculous Meningitis
Indar Kumar Sharawat, Aparna Ramachandran, Prateek Kumar Panda, Vinod Kumar, Poonam Sherwani, Nowneet Kumar Bhat
The American Journal of Tropical Medicine and Hygiene. 2022; 107(6): 1288
[Pubmed] | [DOI]
8 The Outcome of Surgical Intervention (Ventriculoperitoneal Shunt and Endoscopic Third Ventriculostomy) in Patients With Hydrocephalus Secondary to Tuberculous Meningitis: A Systematic Review
Roopa Chalasani, Mastiyage R Goonathilake, Sara Waqar, Sheeba George, Wilford Jean-Baptiste, Amina Yusuf Ali, Bithaiah Inyang, Feeba Sam Koshy, Kitty George, Prakar Poudel, Lubna Mohammed
Cureus. 2022;
[Pubmed] | [DOI]
9 Endoscopic third ventricolustomy as treatment option for normal pressure hydrocephalus
Khalil Komlakh, Hamidreza Oveisi, Seyed Hossein Aghamiri
European Journal of Translational Myology. 2022;
[Pubmed] | [DOI]
10 Current status and challenges in the care of patients with bacterial meningitis in the Philippines: A scoping review
Ferron F. Ocampo, Adrian I. Espiritu, Roland Dominic G. Jamora
Tropical Medicine & International Health. 2022;
[Pubmed] | [DOI]
11 Challenges and Controversies in the Management of Tuberculous Meningitis with Hydrocephalus: A Systematic Review and Sarawak Institution's Experience
Siew-Hong Yiek, Albert Sii-Hieng Wong
Asian Journal of Neurosurgery. 2022;
[Pubmed] | [DOI]
12 Feasibility of awake endoscopic third ventriculostomy in selected patients of obstructive hydrocephalus
Sushant K. Sahoo, Pravin Salunke, Sivashanmugam Dhandapani, Anshul Siroliya, Kiran Jangra
British Journal of Neurosurgery. 2022; : 1
[Pubmed] | [DOI]
13 Complicated Neurotuberclosis with sinus venous thrombosis A case-report
Yousra Ali, Yahia Imam, Hasan S Ahmedullah, Naveed Akhtar, Saadat Kamran, Muna Almaslmani, A Latif Al Khal, Ahmed Own, Dirk Deleu
IDCases. 2022; : e01374
[Pubmed] | [DOI]
14 Paroxysmal sympathetic hyperactivity syndrome in tuberculous meningitis with paradoxical reaction
Andre Marolop Pangihutan Siahaan, Steven Tandean, Rr Suzy Indharty, Bahagia Willibrodus Maria Nainggolan, Martin Susanto
International Journal of Surgery Case Reports. 2022; 99: 107619
[Pubmed] | [DOI]
15 An Elusive Case of Tuberculous Meningitis in a Young Man With Altered Mental Status
Shahid Dodson, Bethanne Bartscherer, Jeffrey Schneider, Gabrielle A. Jacquet
The Journal of Emergency Medicine. 2022;
[Pubmed] | [DOI]
16 Neurotuberculosis: an update
Ajith Cherian, Kesi Chellappan Ajitha, Thomas Iype, K. P. Divya
Acta Neurologica Belgica. 2021; 121(1): 11
[Pubmed] | [DOI]
17 Neuroinfectious Disease Emergencies
Caleb R.S. McEntire, Pria Anand, Anna M. Cervantes-Arslanian
Neurologic Clinics. 2021; 39(2): 565
[Pubmed] | [DOI]
18 Neuro-ophthalmic manifestations of tuberculosis
Rebika Dhiman, Subodh Lakra, Prateek Kumar Panda, Naren Hemachandran, Sanjay Sharma, Rohit Saxena
Eye. 2021;
[Pubmed] | [DOI]
19 Management of tuberculous meningitis in children
H. Simon Schaaf, James A. Seddon
Paediatrics and International Child Health. 2021; : 1
[Pubmed] | [DOI]
20 Bilateral Oculomotor Palsy in Tuberculous Rhomboencephalitis—A Rare Presentation
Paromita Dutta, Vaibhav Nagpal, Kamlesh Anand, Manisha Mishra
Journal of Neurosciences in Rural Practice. 2021; 12(01): 217
[Pubmed] | [DOI]
21 Tracking down the White Plague. Chapter three: Revision of endocranial abnormally pronounced digital impressions as paleopathological diagnostic criteria for tuberculous meningitis
Olga Spekker, David R. Hunt, William Berthon, László Paja, Erika Molnár, György Pálfi, Michael Schultz, Michael C. Burger
PLOS ONE. 2021; 16(3): e0249020
[Pubmed] | [DOI]
22 Giant central nervous system tuberculoma in pediatric patients: surgical case series
Xiao Xiao, Qiang Li, Yan Ju
Child's Nervous System. 2021; 37(9): 2935
[Pubmed] | [DOI]
23 Surgical treatment of post-infectious hydrocephalus in infants
L. Padayachy, L. Ford, N. Dlamini, A. Mazwi
Child's Nervous System. 2021; 37(11): 3397
[Pubmed] | [DOI]
24 Inflammatory hydrocephalus
Stephanie M. Robert, Benjamin C. Reeves, Arnaud Marlier, Phan Q. Duy, Tyrone DeSpenza, Adam Kundishora, Emre Kiziltug, Amrita Singh, Garrett Allington, Seth L. Alper, Kristopher T. Kahle
Child's Nervous System. 2021; 37(11): 3341
[Pubmed] | [DOI]
25 Tuberculous meningitis during infancy: 26 cases in South Turkey among 20 years
Derya Alabaz, Ümmühan Çay
Child's Nervous System. 2021;
[Pubmed] | [DOI]
26 Three Decades of Vellore Grading for Tuberculous Meningitis with Hydrocephalus: A Reappraisal
Vedantam Rajshekhar
Neurology India. 2021; 69(8): 569
[Pubmed] | [DOI]
27 Hydrocephalus in Tuberculous Meningitis - Pearls and Nuances
VimalK Paliwal, RavindraK Garg
Neurology India. 2021; 69(8): 330
[Pubmed] | [DOI]
28 A comparison of Adult and Pediatric Hydrocephalus
Chandrashekhar Deopujari, Chandan Mohanty, Harshal Agrawal, Sonal Jain, Pawan Chawla
Neurology India. 2021; 69(8): 395
[Pubmed] | [DOI]
Geo Jerosh J. R., Sivakumar K., Srisaravanan Jeevarajan
[Pubmed] | [DOI]
30 Role of surgical procedures (VP shunt and ETV) in tuberculous meningitis with hydrocephalus (TBMH): A systematic review
Bharat Bhushan, Vijay Sardana, Prashant Shringi, SeetaRam Yadav, Dilip Maheshwari
Journal of Pediatric Neurosciences. 2021; 16(2): 106
[Pubmed] | [DOI]
31 Cumulative Damage: Cell Death in Posthemorrhagic Hydrocephalus of Prematurity
Riley Sevensky, Jessie C. Newville, Ho Lam Tang, Shenandoah Robinson, Lauren L. Jantzie
Cells. 2021; 10(8): 1911
[Pubmed] | [DOI]
Shivender Sobti, Sachin Singh, Amit Kumar Singh, Laxmi Narayan Gupta, Suryanarayanan Bhaskar, Ajay Choudhary
[Pubmed] | [DOI]
33 Trapped fourth ventricle—treatment options and the role of open posterior fenestration in the surgical management
Gaurav Tyagi, Prashant Singh, Dhanajaya I. Bhat, Dhaval Shukla, Nupur Pruthi, Bhagavatula Indira Devi
Acta Neurochirurgica. 2020; 162(10): 2441
[Pubmed] | [DOI]
34 Ventriculoperitoneal shunt insertion in human immunodeficiency virus infected adults: a systematic review and meta-analysis
James J. M. Loan, Michael T. C. Poon, Steven Tominey, Ncedile Mankahla, Graeme Meintjes, A. Graham Fieggen
BMC Neurology. 2020; 20(1)
[Pubmed] | [DOI]
35 Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets
Jason K. Karimy, Benjamin C. Reeves, Eyiyemisi Damisah, Phan Q. Duy, Prince Antwi, Wyatt David, Kevin Wang, Steven J. Schiff, David D. Limbrick, Seth L. Alper, Benjamin C. Warf?, Maiken Nedergaard, J. Marc Simard, Kristopher T. Kahle
Nature Reviews Neurology. 2020; 16(5): 285
[Pubmed] | [DOI]
36 Chiari malformation and tuberculous meningitis: aetiology and management
Jose Danilo Bengzon Diestro, Jesi Ellen Cueto Bautista, Abdelsimar T Omar, James Garcia Mercado, Philip Asuncion Ramiro
BMJ Case Reports. 2018; : bcr-2018-2
[Pubmed] | [DOI]
37 Ventriculo-peritoneal shunt surgery for tuberculous meningitis: A systematic review
Imran Rizvi,Ravindra Kumar Garg,Hardeep Singh Malhotra,Neeraj Kumar,Eesha Sharma,Chhitij Srivastava,Ravi Uniyal
Journal of the Neurological Sciences. 2017; 375: 255
[Pubmed] | [DOI]
38 Holistic care of complicated tuberculosis in healthcare settings with limited resources
Trevor Duke,Sharon Kasa Tom,Harry Poka,Henry Welch
Archives of Disease in Childhood. 2017; 102(12): 1161
[Pubmed] | [DOI]
39 Old age and hydrocephalus are associated with poor prognosis in patients with tuberculous meningitis
Hai-Jun Huang,Ze-Ze Ren,Yi-Ning Dai,Yong-Xi Tong,Dan-Hong Yang,Mei-Juan Chen,Yi-Cheng Huang,Ming-Shan Wang,Jia-Jie Zhang,Wen-Yuan Song,Hong-Ying Pan
Medicine. 2017; 96(26): e7370
[Pubmed] | [DOI]
40 Tuberculous Meningitis in Children and Adults: New Insights for an Ancient Foe
Alyssa Mezochow,Kiran Thakur,Christopher Vinnard
Current Neurology and Neuroscience Reports. 2017; 17(11)
[Pubmed] | [DOI]
41 Ventriculoperitoneal Shunting Surgery with Open Distal Shunt Catheter Placement in the Treatment of Hydrocephalus
Yang Zhang,Xiaobo Zhu,Jinchuan Zhao,Kun Hou,Xianfeng Gao,Yang Sun,Wei Wang,Xiaona Zhang
Cell Biochemistry and Biophysics. 2015; 73(2): 533
[Pubmed] | [DOI]
42 Surgery for brain tuberculosis: a review
Vedantam Rajshekhar
Acta Neurochirurgica. 2015; 157(10): 1665
[Pubmed] | [DOI]
43 Tubercular meningitis with hydrocephalus with HIV co-infection: role of cerebrospinal fluid diversion procedures
Raman Mohan Sharma,Nupur Pruthi,Arivazhagan Arimappamagan,Sampath Somanna,Bhagavathula Indira Devi,Paritosh Pandey
Journal of Neurosurgery. 2015; 122(5): 1087
[Pubmed] | [DOI]
44 Endoscopic third ventriculostomy for post-inflammatory hydrocephalus in pediatric patients: is it worth a try?
Alaa Raouf,Ihab Zidan,Eshra Mohamed
Neurosurgical Review. 2014;
[Pubmed] | [DOI]
45 Bacterial Infections of the Central Nervous System
Katharina M. Busl,Thomas P. Bleck
Current Infectious Disease Reports. 2013;
[Pubmed] | [DOI]
46 Surgery in hydrocephalus of tubercular origin: challenges and management
Apoorva Kumar,Kulwant Singh,Vivek Sharma
Acta Neurochirurgica. 2013; 155(5): 869
[Pubmed] | [DOI]
47 Rapidly progressive dementia and ataxia in an elderly man
Ahmed, R.M. and Halmagyi, G. and Rodriguez, M.L.
Practical Neurology. 2013; 13(3): 165-173
48 Drug-resistant tuberculous meningitis
Garg, R.K. and Jain, A. and Malhotra, H.S. and Agrawal, A. and Garg, R.
Expert Review of Anti-Infective Therapy. 2013; 11(6): 605-621
49 The role of ventriculoperitoneal shunt placement in patients of tubercular meningitis with hydrocephalus in poor neurological grade: A prospective study in the pediatric population and review of literature
Savardekar, A. and Chatterji, D. and Singhi, S. and Mohindra, S. and Gupta, S. and Chhabra, R.
Childćs Nervous System. 2013; 29(5): 719-725
50 Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis
Raut, T. and Garg, R.K. and Jain, A. and Verma, R. and Singh, M.K. and Malhotra, H.S. and Kohli, N. and Parihar, A.
Journal of Infection. 2013; 66(4): 330-337
51 Endoscopic challenges and applications in tuberculous meningitis
Figaji, A.A. and Fieggen, A.G.
World Neurosurgery. 2013; 79(2 SUPPL.): S24.e9-S24.e14
52 Hidrocefalia por meningitis tuberculosa con líquido cefalorraquídeo ventricular normal
A. Martínez-Antón,S. Montoro,T. Gavela,F. Ruiz-Juretschke
Anales de Pediatría. 2013; 79(2): 128
[Pubmed] | [DOI]
53 Hydrocephalus in tuberculous meningitis: Incidence, its predictive factors and impact on the prognosis
Tushar Raut,Ravindra Kumar Garg,Amita Jain,Rajesh Verma,Maneesh Kumar Singh,Hardeep Singh Malhotra,Neera Kohli,Anit Parihar
Journal of Infection. 2013; 66(4): 330
[Pubmed] | [DOI]
54 Tuberculous meningitis and hydrocephalus
Miguel Gelabert-González, Eduardo Aran-Echabe
Journal of Infection. 2013;
[VIEW] | [DOI]
55 Tuberculous meningitis and hydrocephalus
Ravindra Kumar Garg,Tushar Raut,Hardeep Singh Malhotra,Amita Jain
Journal of Infection. 2013; 66(6): 541
[Pubmed] | [DOI]
56 Endoscopic Challenges and Applications in Tuberculous Meningitis
Anthony A. Figaji,A. Graham Fieggen
World Neurosurgery. 2013; 79(2): S24.e9
[Pubmed] | [DOI]
57 Rapidly progressive dementia and ataxia in an elderly man
R. M. Ahmed,G. M. Halmagyi,M. L. Rodriguez
Practical Neurology. 2013; 13(3): 165
[Pubmed] | [DOI]
58 Drug-resistant tuberculous meningitis
Ravindra K Garg,Amita Jain,Hardeep S Malhotra,Avinash Agrawal,Rajiv Garg
Expert Review of Anti-infective Therapy. 2013; 11(6): 605
[Pubmed] | [DOI]
59 A Review of the Neurological and Neurosurgical Implications of Tuberculosis in Children
Sudhakar Vadivelu,Sabih Effendi,Jeffrey R. Starke,Thomas G. Luerssen,Andrew Jea
Clinical Pediatrics. 2013; 52(12): 1135
[Pubmed] | [DOI]
60 Tuberculous meningitis in adults: a review of a decade of developments focusing on prognostic factors for outcome
Flavia Brancusi,Jeremy Farrar,Dorothee Heemskerk
Future Microbiology. 2012; 7(9): 1101
[Pubmed] | [DOI]
61 Prognostic Value of Computed Tomography-Evident Cerebral Infarcts in Adult Patients with Tuberculous Meningitis and Hydrocephalus Treated with an External Ventricular Drain
Tiago Clemente Morgado,Max Kinsky,Henri Carrara,Sally Rothemeyer,Patrick Semple
World Neurosurgery. 2012;
[Pubmed] | [DOI]
62 Ventriculocholecysto shunt: A solution to recurrent shunt complications in comorbid post-tubercular hydrocephalus with tubercular adhesive peritonitis
Lyngdoh, B.T. and Islam, M.S.
Acta Neurochirurgica. 2012; 154(12): 2267-2270
63 Abnormal head movement in a patient with tuberculous meningitis
Garg, R.K. and Singh, S.K. and Malhotra, H.S. and Singh, M.K.
BMJ Case Reports. 2012;
64 Tuberculous meningitis in adults: A review of a decade of developments focusing on prognostic factors for outcome
Brancusi, F. and Farrar, J. and Heemskerk, D.
Future Microbiology. 2012; 7(9): 1101-1116
65 Tuberculous meningitis, an unusual presentation in a young lady
Chohan, T. and Jain, A. and Saeed, M. and Saeed, S.A. and Dharmasena, U.K.
BMJ Case Reports. 2012;
66 Endoscopic third ventriculostomy in tuberculous meningitis needs more evidence
Misra, U.K. and Kalita, J. and Prabhakar, S. and Chakravarty, A. and Kochar, D. and Nair, P.P.
Annals of Indian Academy of Neurology. 2012; 15(3): 233
67 Management of hydrocephalus in tuberculous meningitis
Bhaskar, S.
Annals of Indian Academy of Neurology. 2012; 15(3): 231
68 Ventriculoperitoneal shunt complications needing shunt revision in children: A review of 5 years of experience with 48 revisions
Ghritlaharey, R.K. and Budhwani, K.S. and Shrivastava, D.K. and Srivastava, J.
African Journal of Paediatric Surgery. 2012; 9(1): 32-39
69 Ventriculocholecysto shunt: a solution to recurrent shunt complications in comorbid post-tubercular hydrocephalus with tubercular adhesive peritonitis
Bernard Trench Lyngdoh,Mohammad Shamsul Islam
Acta Neurochirurgica. 2012; 154(12): 2267
[Pubmed] | [DOI]
70 Central nervous system infections and the neurosurgeon: A perspective
Muzumdar, D.
International Journal of Surgery. 2011; 9(2): 113-116
71 Central nervous system tuberculosis
Cherian, A., Thomas, S.V.
African Health Sciences. 2011; 11(1): 116-127
72 Management of post-tubercular hydrocephalus
Vivek Tandon, Ashok Kumar Mahapatra
Child s Nervous System. 2011; 27(10): 1699
[VIEW] | [DOI]
73 Hydrocephalus in toddlers: the place of shunts in sub-Sahara African countries
Vincent de paul Djientcheu, Seraphin Nguefack, T. Olivier Mouafo, A. Stephane Mbarnjuk, T. Yves Yamgoue, Figuim Bello, Giles Kagmeni, Elie Mbonda, Benedict Rilliet
Child s Nervous System. 2011;
[VIEW] | [DOI]
74 Role of ventriculoperitoneal shunt surgery in grade IV tubercular meningitis with hydrocephalus
Jing Peng, Xiaolu Deng, Fang He, Ahmed Omran, Ciliu Zhang, Fei Yin, Jingping Liu
Child s Nervous System. 2011;
[VIEW] | [DOI]
75 Endoscopic third ventriculostomy for hydrocephalus: A review of indications, outcomes, and complications
Moorthy, R.K. and Rajshekhar, V.
Neurology India. 2011; 59(6): 848-854
76 Endoscopic third ventriculostomy in tubercular meningitis with hydrocephalus
Yadav, Y.R. and Parihar, V. and Agrawal, M. and Bhatele, P.R.
Neurology India. 2011; 59(6): 855-860
77 CSF shunt complications in infants - An experience from Pakistan
Bakhsh, A.
Pediatric Neurosurgery. 2011; 47(2): 93-98
78 Brain tuberculomas, tubercular meningitis, and post-tubercular hydrocephalus in children
Chatterjee, S.
Journal of Pediatric Neurosciences. 2011; 6(3 SUPPL.): S96-S100
79 Hydrocephalus Indian scenario A review
Venkataramana, N.K.
Journal of Pediatric Neurosciences. 2011; 6(3 SUPPL.): S11-S22
80 Treatment of central nervous system tuberculosis infections and neurological complications of tuberculosis treatment
van der Harst, J.J. and Luijckx, G.J.
Current Pharmaceutical Design. 2011; 17(27): 2940-2947
81 Symptomatic retethering of the spinal cord after section of a tight filum terminale
Yong, R.L. and Habrock-Bach, T. and Vaughan, M. and Kestle, J.R. and Steinbok, P.
Neurosurgery. 2011; 68(6): 1594-1601
82 Does CSF composition predict shunt malfunction in tuberculous meningitis?
Ambekar, S. and Dwarakanath, S. and Chandramouli, B.A. and Sampath, S. and Indira Devi, B. and Pandey, P.
Indian Journal of Tuberculosis. 2011; 58(2): 77-81
83 Central nervous system infections and the neurosurgeon: A perspective
Dattatraya Muzumdar
International Journal of Surgery. 2011; 9(2): 113
[Pubmed] | [DOI]
84 Symptomatic Retethering of the Spinal Cord After Section of a Tight Filum Terminale
Raymund L Yong,Tracey Habrock-Bach,Mariko Vaughan,John R Kestle,Paul Steinbok
Neurosurgery. 2011; 68(6): 1594
[Pubmed] | [DOI]
85 CSF Shunt Complications in Infants – An Experience from Pakistan
Ahmed Bakhsh
Pediatric Neurosurgery. 2011; 47(2): 93
[VIEW] | [DOI]
86 Protective Therapy with Novel Chromone Derivative against &lt;i&gt;Leishmania donovani&lt;/i&gt; Infection Induces Th1 Response in vivo
Suvadip Mallick, Aritri Dutta, Joydip Ghosh, Sourav Maiti, Ajay Kumar Mandal, Rajat Banerjee, Chandrakanta Bandyopadhyay, Chiranjib Pal
Chemotherapy. 2011; 57(5): 388
[VIEW] | [DOI]
87 Arnold-Chiari malformation
Rajaraman Durai,Carl Fernandes,Philip CH Ng
British Journal of Hospital Medicine. 2010; 71(3): 173
[Pubmed] | [DOI]
88 HIV-associated tuberculous meningitis – diagnostic and therapeutic challenges
Suzaan Marais,Dominique J. Pepper,Ben J. Marais,M. Estée Török
Tuberculosis. 2010; 90(6): 367
[Pubmed] | [DOI]
89 The neurosurgical and acute care management of tuberculous meningitis: Evidence and current practice
Anthony A. Figaji,A. Graham Fieggen
Tuberculosis. 2010; 90(6): 393
[Pubmed] | [DOI]
90 Meningitis and encephalitis in adolescents
Garrett Hunt, W.
Adolescent Medicine: State of the Art Reviews. 2010; 21(2): 287-317
91 Use of endoscopic third ventriculostomy in hydrocephalus of tubercular origin
Sanat Bhagwati, Nirav Mehta, Suneel Shah
Child s Nervous System. 2010; 26(12): 1675-1682
92 The neurosurgical and acute care management of tuberculous meningitis: Evidence and current practice
Figaji, A.A., Fieggen, A.G.
Tuberculosis. 2010; 90(6): 393-400
93 HIV-associated tuberculous meningitis - Diagnostic and therapeutic challenges
Marais, S., Pepper, D.J., Marais, B.J., Török, M.E.
Tuberculosis. 2010; 90(6): 367-374
94 Arnold-Chiari malformation
Durai, R., Fernandes, C., Ng, P.C.H.
British Journal of Hospital Medicine. 2010; 71(3): 173
95 Management of hydrocephalus in patients with tuberculous meningitis
Yadav, Y.R., Parihar, V.
Neurology India. 2009; 57(5): 691


Print this article  Email this article
Previous article Next article
Online since 20th March '04
Published by Wolters Kluwer - Medknow