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Year : 2010  |  Volume : 58  |  Issue : 2  |  Page : 309--311

Bilateral Lhermitte-Duclos disease

1 2nd Department of Neurosurgery, Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey
2 Department of Neuropathology, Istanbul Medicine Faculty, Istanbul University, Istanbul, Turkey

Correspondence Address:
Hikmet Turan Suslu
Dr. Lutfi Kirdar Kartal Egitim ve Arastirma Hastanesi, Kartal, Istanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.63799

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Lhermitte-Duclos disease (LDD) is a pathologic entity with progrediating, diffuse hypertrophy chiefly of the stratum granulosum of the cerebellum. Typically LDD is a unilateral lesion of the cerebellum or in vermis. Here we report a case of LDD with bilateral lesions of cerebellar hemispheres managed surgically. A 28-year-old woman presented with one-year history of progressive headache, nausea, vomiting, and blurred vision. Neurologic examination revealed a bilateral mild papilledema, mild dysmetria, and dysdiadochokinesia. The cerebellar lesions caused moderate mass effect in posterior fossa with hydrocephalus, and Chiari type I malformation. We performed the suboccipital-retrosigmoid approach, and removed completely the left intracerebellar mass. Symptoms related to elevated intracranial pressure disappeared in a short period postoperatively.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow