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Year : 2011  |  Volume : 59  |  Issue : 6  |  Page : 887--890

Dual pathology of corticobasal degeneration and Parkinson's disease in a patient with clinical features of progressive supranuclear palsy

1 Department of Neurology, Nambour General Hospital, QLD, Australia
2 Department of Geriatrics, Nambour General Hospital, QLD, Australia
3 Department of Anatomical Pathology, Royal Brisbane and Women's Hospital, QLD, Australia

Correspondence Address:
Tomin Mooney
Department of Neurology, Level 2, Block 6, Nambour General Hospital, 33 Hospital Road, Nambour, QLD 4560
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.91371

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Corticobasal degeneration and Parkinson's disease are pathologically distinct disorders with unique histological and biochemical features of a tauopathy and a-synucleinopathy respectively. We report the first case of co-occurrence of these pathologies in the same patient. Convergence of such distinctly separate neuropathology in the same brain highlights the need for extensive brain banking and further research in supporting the hypothesis that tauopathies and a-synucleinopathies might share common pathogenic mechanisms.


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Online since 20th March '04
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