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 CASE REPORT
Year : 2012  |  Volume : 60  |  Issue : 6  |  Page : 635--637

Reversible cerebral vasoconstriction syndrome in a patient with systemic lupus erythematosus


1 Department of Neurology, Malabar Institute of Medical Sciences, Calicut, Kerala, India
2 Department of Rheumatology, Malabar Institute of Medical Sciences, Calicut, Kerala, India
3 Department of Radiology, Malabar Institute of Medical Sciences, Calicut, Kerala, India

Correspondence Address:
V V Ashraf
Department of Neurology, Malabar Institute of Medical Sciences, Govindapuram PO,Calicut - 673 016, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.105200

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A 42-year-old woman, a diagnosed case of systemic lupus erythematosus (SLE), developed severe headache followed by left hemiparesis and cortical blindness. Magnetic resonance imaging (MRI) of brain demonstrated right parieto-occipital infarct and the patient was initiated on high-dose steroids and antiplatelet agents with which the patient had clinical and radiological deterioration. Magnetic Resonance angiography showed severe narrowing of bilateral anterior, middle, and posterior cerebral arteries (PCA) suggestive of reversible cerebral vasoconstriction syndrome (RCVS). Patient was treated with IV nimodipine and she recovered over a period of 2 weeks. Repeat MR-angiography done on day-30 was normal. The diagnosis of RCVS in patients with SLE is of practical importance, because treatment and prognosis for SLE-associated cerebral vasculitis differ strongly from the treatment of RCVS. Empirical high-dose glucocorticoid therapy should be avoided in patients with typical features of RCVS.






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Online since 20th March '04
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